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Selective estrogen receptor modulators

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Hormonal agents (16)
Systemic hormonal preparations (16)
Drugs acting on the genito-urinary system (10)
Sex hormones (9)
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Estrogens (5)
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Alkenes (3)
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Five-membered rings (3)
Pyrrolidines (3)
Synthetic estrogens (3)
Triphenylethylenes (3)
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Selective estrogen receptor degraders (1)
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Bisphenol A (27100-33-0, 80-05-7)  
diphenylolpropane  ·  4,4'-dihydroxy-2,2-diphenylpropane  ·  2,2-bis(4-hydroxyphenyl)propane
Bisphenol A (BPA) is an organic synthetic compound with the chemical formula (CH3)2C(C6H4OH)2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. It is a colorless solid that is soluble in organic solvents, but poorly soluble in water. It has been in commercial use since 1957.
Phenytoin (57-41-0, 630-93-3)  
Dilantin  ·  Diphenylhydantoin  ·  Phenytoin Sodium
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. It is useful for the prevention of tonic-clonic seizures and partial seizures, but not absence seizures. The intravenous form is used for status epilepticus that does not improve with benzodiazepines.
raloxifene (84449-90-1)  
Raloxifene, sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer. It is taken by mouth. Side effects of raloxifene include hot flashes, leg cramps, and an increased risk of blood clots and other cardiovascular events such as stroke.
chlorotrianisene (569-57-3)  
Chlorotrianisene (INN, USAN, BAN; brand names Tace, Estregur, Anisene, Clorotrisin, Merbentyl, Triagen, many others; also known as CTA; tri-p-anisylchloroethylene, TACE, or tris(p-methoxyphenyl)chloroethylene) is a synthetic nonsteroidal estrogen of the triphenylethylene group which was formerly used for the treatment of menopausal symptoms, estrogen deficiency, and prostate cancer before being discontinued. It was approved in the United States as TACE in 1952, and was introduced throughout Europe subsequently. CTA was the first estrogenic compound of the triphenylethylene series to be introduced.
Bazedoxifene (198481-32-2)  
Bazedoxifene, or bazedoxifene acetate, is a medication for bone problems and possibly (pending more study) for cancer. It is a third-generation selective estrogen receptor modulator (SERM). Since late 2013 it has had U.S.
2-HYDROXYESTRONE (362-06-1)  
2-Hydroxyestrone (2-OHE1), also known as estra-1,3,5(10)-trien-2,3-diol-17-one, is an endogenous, naturally occurring catechol estrogen and a major metabolite of estrone and estradiol. It is formed irreversibly from estrone in the liver and to a lesser extent in other tissues via 2-hydroxylation mediated by cytochrome P450 enzymes, mainly the CYP3A and CYP1A subfamilies. 2-OHE1 is the most abundant catechol estrogen in the body.
2-Hydroxyestradiol (362-05-0)  
2-Hydroxyestradiol (2-OHE2), also known as estra-1,3,5(10)-triene-2,3,17β-triol, is an endogenous steroid, catechol estrogen, and metabolite of estradiol, as well as a positional isomer of estriol.
Lasofoxifene (180916-16-9)  
Lasofoxifene, sold under the brand name Fablyn, is a nonsteroidal selective estrogen receptor modulator (SERM) which is marketed by Pfizer in Lithuania and Portugal for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND). It also appears to have had a statistically significant effect of reducing breast cancer in women according to a study published in The Journal of the National Cancer Institute.
cyclofenil (2624-43-3)  
Cyclophenil  ·  F 6066  ·  Ondogyne
Cyclofenil (INN, USAN, BAN) (brand names Fertodur, Menopax, Ondonid, Ondogyne, Sexovid, others) is a selective estrogen receptor modulator (SERM) used as a gonadotropin stimulant which is or has been marketed in Europe, South Korea, Mexico, and Brazil, among other countries. Cyclofenil was first introduced in 1970 under the brand name Ondogyne in France. Subsequently, it was introduced under the brand names Sexovid in Japan in 1972, Ondonvid in the United Kingdom in 1972, and Fertodur in West Germany in 1972 and Italy in 1974.
Levormeloxifene (31477-60-8, 78994-23-7)  
Levormeloxifene (INN; developmental code names 6720-CDRI, NNC-460020) is a selective estrogen receptor modulator (SERM) which was being developed as an alternative to estrogen replacement therapy for the treatment and prevention of postmenopausal bone loss but did not complete development and hence was never marketed. The development was stopped because of a high incidence of gynecological side effects during clinical trials. Levormeloxifene is the levorotatory enantiomer of ormeloxifene, which, in contrast, has been marketed, though rather as a hormonal contraceptive.
Ormeloxifene (31477-60-8, 51423-20-2)  
Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators, or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a nonsteroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it is currently marketed there under the trade name Saheli.
Broparestrol (479-68-5, 22393-63-1)  
LN 1643  ·  alpha-(4-ethyl)phenyl-alpha'-bromo trans-stilbene  ·  LN 2299

Related Results:
raloxifene (84449-90-1)  
Raloxifene, sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer. It is taken by mouth. Side effects of raloxifene include hot flashes, leg cramps, and an increased risk of blood clots and other cardiovascular events such as stroke.
Tamoxifen citrate (54965-24-1)  
Tamoxifen  ·  Nolvadex  ·  ICI 46,474
Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men. It is also being studied for other types of cancer. It has been used for Albright syndrome.
tamoxifen (13002-65-8, 10540-29-1)  
Nolvadex  ·  Tamoxifen Citrate  ·  ICI 46,474
3,20-Allopregnanedione (566-65-4)  
5alpha-Pregnane-3,20-dione  ·  3,20-Allopregnanedione, (5beta,13alpha,17alpha)-Isomer  ·  5 alpha-Pregnane-3,20-dione
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