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Tropane alkaloids

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Drugs acting on the nervous system (23)
Psychoactive drugs (23)
Tropanes (23)
Alkaloids (11)
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Drugs acting on the gastrointestinal system and metabolism (6)
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Three-membered rings (6)
Alkaloid (5)
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Drugs acting on the cardiovascular system (4)
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Alkenes (2)
Carboxylic acids (2)
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Hyoscine (51-34-3, 138-12-5)  
Scopolamine  ·  Scopolamine Hydrobromide  ·  Transderm Scop
ATROPINE (13269-35-7, 51-55-8, 101-31-5, 5908-99-6)  
Atropine Sulfate  ·  Atropine Sulfate Anhydrous  ·  Atropin Augenöl
Atropine is a medication to treat certain types of nerve agent and pesticide poisonings as well as some types of slow heart rate and to decrease saliva production during surgery. It is typically given intravenously or by injection into a muscle. Eye drops are also available which are used to treat uveitis and early amblyopia.
scopolamine (51-34-3)  
Hyoscine  ·  Scopolamine Hydrobromide  ·  Transderm Scop
L-Hyoscyamine (51-55-8, 101-31-5, 5908-99-6)  
Hyoscyamine  ·  Hyoscyamine Sulfate  ·  Anaspaz
hyoscyamine (5908-99-6, 101-31-5)  
Hyoscyamine (also known as daturine) is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane (Hyoscyamus niger), mandrake (Mandragora officinarum), jimsonweed (Datura stramonium), tomato (Solanum lycopersicum) and deadly nightshade (Atropa belladonna). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.
Cystospaz (13269-35-7, 51-55-8, 101-31-5)  
Hyoscyamine  ·  Hyoscyamine Sulfate  ·  Anaspaz
Hyoscyamine (also known as daturine) is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane (Hyoscyamus niger), mandrake (Mandragora officinarum), jimsonweed (Datura stramonium), tomato (Solanum lycopersicum) and deadly nightshade (Atropa belladonna). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.
(R)-atropine (13269-35-7, 101-31-5)  
Hyoscyamine (also known as daturine) is a tropane alkaloid. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane (Hyoscyamus niger), mandrake (Mandragora officinarum), jimsonweed (Datura stramonium), tomato (Solanum lycopersicum) and deadly nightshade (Atropa belladonna). It is the levorotary isomer of atropine (third of the three major nightshade alkaloids) and thus sometimes known as levo-atropine.
Tropinone (532-24-1)  
3-tropinone hydrobromide  ·  3-tropinone  ·  3-tropinone hydrochloride
Tropinone is an alkaloid, famously synthesised in 1917 by Robert Robinson as a synthetic precursor to atropine, a scarce commodity during World War I. Tropinone and the alkaloids cocaine and atropine all share the same tropane core structure. Its corresponding conjugate acid at pH 7.3 major species is known as tropiniumone.
tropan-3-one (532-24-1)  
Tropinone is an alkaloid, famously synthesised in 1917 by Robert Robinson as a synthetic precursor to atropine, a scarce commodity during World War I. Tropinone and the alkaloids cocaine and atropine all share the same tropane core structure. Its corresponding conjugate acid at pH 7.3 major species is known as tropiniumone.
racanisodamine (55869-99-3)  
anisodamine  ·  anisodamine hydrobromide  ·  6-hydroxyhyoscyamine
Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt. Eye drops at 0.5% concentration for slowing the progression is also available in China.
anisodamine (55869-99-3)  
Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt. Eye drops at 0.5% concentration for slowing the progression is also available in China.
Methylecgonidine (43021-26-7, 50373-10-9)  
Methylecgonidine (anhydromethylecgonine; anhydroecgonine methyl ester; AEME) is a chemical intermediate derived from ecgonine or cocaine. Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful biomarker to specifically test for use of crack cocaine, as opposed to powder cocaine which does not form methylecgonidine as a metabolite. Methylecgonidine has a relatively short half-life of 18–21 minutes, after which it is metabolised to ecgonidine, meaning that the relative concentrations of the two compounds can be used to estimate how recently crack cocaine has been smoked.
CHEMBL412663 (43021-26-7)  
Methylecgonidine (anhydromethylecgonine; anhydroecgonine methyl ester; AEME) is a chemical intermediate derived from ecgonine or cocaine. Methylecgonidine is a pyrolysis product formed when crack cocaine is smoked, making this substance a useful biomarker to specifically test for use of crack cocaine, as opposed to powder cocaine which does not form methylecgonidine as a metabolite. Methylecgonidine has a relatively short half-life of 18–21 minutes, after which it is metabolised to ecgonidine, meaning that the relative concentrations of the two compounds can be used to estimate how recently crack cocaine has been smoked.
anisodine (52646-92-1)  
Anisodine, also known as daturamine and α-hydroxyscopolamine, is an antispasmodic and anticholinergic drug used in the treatment of acute circulatory shock in China. It is a tropane alkaloid and is found naturally in species of the Solanaceae family of plants. Anisodine acts as a muscarinic acetylcholine receptor antagonist and α1-adrenergic receptor agonist.
Scopine (498-45-3)  
Scopine is a tropane alkaloid found in a variety of plants including Mandragora root, Senecio mikanoides (Delairea odorata), Scopolia carniolica, and Scopolia lurida. Scopine can be prepared by the hydrolysis of scopolamine. It can also be prepared in three steps from N-methoxycarbonylpyrrole and 1,1,3,3-tetrabromoacetone; the reagents are combined in a [4+3] cycloaddition, followed by a diastereoselective reduction with diisobutylaluminum hydride, and finally a Prilezhaev epoxidation with trifluoroperacetic acid affords scopine.
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