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Typical antipsychotics

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Antipsychotics (38)
Dopamine antagonists (38)
Drugs acting on the nervous system (38)
Psychoactive drugs (38)
Psychopharmacology (38)
Cyclic compounds (33)
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Piperidines (11)
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Nervous system drug (9)
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Chlorpromazine (34468-21-8, 50-53-3)  
Thorazine  ·  Chlorpromazine Hydrochloride  ·  Largactil
Chlorpromazine (CPZ), marketed under the trade names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar disorder, attention deficit hyperactivity disorder, nausea and vomiting, anxiety before surgery, and hiccups that do not improve following other measures.
thioridazine (50-52-2)  
Mellaril  ·  Thioridazine Hydrochloride  ·  Melleril
Thioridazine (Mellaril or Melleril) is a piperidine typical antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. The branded product was withdrawn worldwide in 2005 because it caused severe cardiac arrhythmias. However, generic versions are still available in the US.
perphenazine (58-39-9)  
Trilafon  ·  Perfenazine  ·  Chlorpiprazine
Perphenazine is a typical antipsychotic drug. Chemically, it is classified as a piperazinyl phenothiazine. Originally marketed in the US as Trilafon, it has been in clinical use for decades.
FLUPHENAZINE (69-23-8)  
Prolixin  ·  Fluphenazine Hydrochloride  ·  Flufenazin
Fluphenazine, sold under the brand names Prolixin among others, is an antipsychotic medication. It is used in the treatment of chronic psychoses such as schizophrenia, and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. It is given by mouth, injection into a muscle, or just under the skin.
haloperidol (61788-97-4, 52-86-8)  
Haldol
Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, nausea and vomiting, delirium, agitation, acute psychosis, and hallucinations in alcohol withdrawal. It may be used by mouth, as an injection into a muscle, or intravenously.
trifluoperazine (117-89-5)  
Stelazine  ·  Trifluoperazine Hydrochloride  ·  Trifluperazine
Trifluoperazine, sold under a number of brand names, is a typical antipsychotic primarily used to treat schizophrenia. It may also be used short term in those with generalized anxiety disorder but is less preferred to benzodiazepines. It is of the phenothiazine chemical class.
Levomepromazine (7104-38-3, 60-99-1)  
Methotrimeprazine  ·  Levopromazine  ·  Tizercine
mesoridazine (5588-33-0)  
Serentil
Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a metabolite of thioridazine. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure.
triflupromazine (146-54-3)  
Trifluopromazine  ·  Fluopromazine  ·  Bristol Myers Squibb Brand of Triflupromazine Hydrochloride
Triflupromazine (Vesprin) is an antipsychotic medication of the phenothiazine class. Among different effects of triflupromazine indication for use of this drug is severe emesis. Due to its potential side effects (triflupromazine has higher risk for side effects than many other antipsychotics) it is not gold standard in antiemetic therapy.
BUTAPERAZINE (653-03-2)  
butyrylperazine
Butaperazine (Repoise, Tyrylen) is a typical antipsychotic of the phenothiazine class.
pimozide (2062-78-4)  
Orap  ·  Antalon  ·  Orap forte
Pimozide (sold under the brand name Orap) is an antipsychotic drug of the diphenylbutylpiperidine class. It was discovered at Janssen Pharmaceutica in 1963. It has a high potency compared to chlorpromazine (ratio 50-70:1).
ACEPROMAZINE (3598-37-6, 61-00-7)  
Acetylpromazine  ·  Acepromazine Maleate  ·  Acetazine
Acepromazine, acetopromazine or acetylpromazine (more commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was tested in humans in the 1950s as an antipsychotic, but is now almost exclusively used on animals as a sedative and antiemetic. Its closely related analogue, chlorpromazine, is still used as an antipsychotic in humans.
Pipotiazine (39860-99-6)  
pipothiazine  ·  19366-RP  ·  19366 RP
Pipotiazine (Piportil), also known as pipothiazine, is a typical antipsychotic of the phenothiazine class used in the United Kingdom and other countries for the treatment of schizophrenia. Its properties are similar to those of chlorpromazine. A 2004 systematic review investigated its efficacy for people with schizophrenia:
Thioproperazine (316-81-4)  
Majeptil  ·  thioproperazine mesylate
Thioproperazine, sold under the brand name Majeptil, is a typical antipsychotic of the phenothiazine group which is used as a tranquilizer, antiemetic, sedative, and in the treatment of schizophrenia.
sulpiride (15676-16-1)  
Sulp  ·  neogama  ·  Deponerton
Sulpiride (brand names Dogmatil ( DE, HK, SG, PH), Dolmatil (IE, UK), Eglonyl (RU, ZA), Espiride (ZA), Modal (IL), Prometar (UY), Sulpor (UK) and others) is an atypical antipsychotic drug (although some texts have referred to it as a typical antipsychotic) of the benzamide class used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and sometimes used in low dosage to treat anxiety and mild depression. Sulpiride is commonly used in Asia, Central America, Europe, South Africa and South America. Levosulpiride is its purified levo-isomer and is sold in India for similar purpose.
periciazine (2622-26-6)  
pericyazine  ·  propericiazine  ·  Aolept
Periciazine (INN), also known as pericyazine (BAN) or propericiazine, is a drug that belongs to the phenothiazine class of typical antipsychotics. Pericyazine is not approved for sale in the United States. It is commonly sold in Canada and Russia under the tradename Neuleptil and in United Kingdom and Australia under the tradename Neulactil.
ACETOPHENAZINE (2751-68-0)  
Acetophenazine (Tindal) is a typical antipsychotic of the phenothiazine class.
Fluspirilene (1841-19-6)  
Imap  ·  Fluspirilen beta  ·  Hexal Brand of Fluspirilene
Fluspirilene (Redeptin, Imap, R6218) is a diphenylbutylpiperidine typical antipsychotic drug, used for the treatment of schizophrenia. It is administered intramuscularly. It was discovered at Janssen Pharmaceutica in 1963.
THIOPROPAZATE (84-06-0)  
thiopropazate dihydrochloride  ·  thiopropazate, ion (+1)
Thiopropazate (Artalan, Dartal, Dartalan, Dartan) is a typical antipsychotic of the phenothiazine class. It is a prodrug to perphenazine. Thiopropazate is manufactured by Searle (US, UK) & Boehringer Mannheim (Germany) Thiopropazate is sold by Chembase, AAA Chemistry, ZINC, AKos Consulting & Solutions, Boc Sciences, ChemFrog, and ChemMol
PERAZINE (84-97-9, 5317-37-3)  
Perazine Dihydrochloride  ·  Taxilan  ·  Perazine Maleate (1:1)
Perazine (Taxilan) is a moderate-potency typical antipsychotic of the phenothiazine class. It is quite similar to chlorpromazine, and acts as a dopamine antagonist. A 2014 systematic review compared it with other antipsychotic drugs:
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