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aksci.com, Drugs acting on the musculoskeletal system

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Anti-inflammatory and antirheumatic products (43)
Anti-inflammatory agents (39)
Pharmaceuticals (38)
Drugs acting on the nervous system (36)
Analgesics (29)
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Nonsteroidal anti-inflammatory drugs (28)
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Musculoskeletal system drug (20)
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Antineoplastic and immunomodulating drugs (9)
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Diclofenac (15307-86-5)  
Voltaren  ·  Diclofenac Sodium  ·  SR 38
Diclofenac (sold under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. It is supplied as or contained in medications under a variety of trade names. The name "diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid.
Probenecid (57-66-9)  
Benemid  ·  Benuryl  ·  Probenecid Weimer
Probenecid, also sold under the brandname Probalan, is a medication that increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.
Prednisolone (50-24-8)  
Predate  ·  Predonine  ·  DiAdresonF
Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. It is used by mouth, injection into a vein, as a skin cream, and as eye drops.
Methotrexate (59-05-2)  
Amethopterin  ·  Methotrexate Sodium  ·  Mexate
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma.
Phenylbutazone (50-33-9)  
Butazolidin  ·  Butadione  ·  Butapyrazole
Phenylbutazone, often referred to as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals. In the United States and United Kingdom it is no longer approved for human use (except for ankylosing spondylitis, because no other treatment is available), as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. This drug was implicated in the 2013 meat adulteration scandal.
5-Aminosalicylic acid (89-57-6)  
Mesalamine  ·  Asacol  ·  Pentasa
Mesalazine (INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn's disease. It is sold in an oral form to maintain remission in Crohn's disease, and as a rectal suppository and an enema for the lower bowel conditions. It is generic and sold under many brand names worldwide, and there are many formulations.
ibuprofen (15687-27-1)  
Motrin  ·  Rufen  ·  Nuprin
Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation. This includes painful menstrual periods, migraines, and rheumatoid arthritis. About 60% of people improve with any given NSAID, and it is recommended that if one does not work then another should be tried.
triamcinolone (51855-44-8, 124-94-7)  
Aristocort  ·  Volon
Triamcinolone is an intermediate-acting synthetic glucocorticoid given orally, by injection, by inhalation, or as a topical ointment or cream.
celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
oxaprozin (21256-18-8)  
Daypro  ·  Rhoxal-oxaprozin  ·  Apo-Oxaprozin
Oxaprozin, also known as Oxaprozinum, (sold under the names: Daypro, Dayrun, Duraprox) is a nonsteroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically, it is a propionic acid derivative. It is available in 600 mg tablets.
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
D-Penicillamine (52-67-5)  
Penicillamine  ·  Cuprimine  ·  Dimethylcysteine
Penicillamine, sold under the trade names of Cuprimine among others, is a medication primarily used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and lead poisoning. It is taken by mouth.
piroxicam (36322-90-4)  
Feldene  ·  CP-16171  ·  CP16171
Valdecoxib (181695-72-7)  
Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. Valdecoxib was manufactured and marketed under the brand name Bextra by G.
ketorolac (66635-83-4, 74103-06-3)  
Ketorolac, sold under the brand name Toradol among others, is a nonsteroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, used as an analgesic. It is considered a first-generation NSAID. Ketorolac acts by inhibiting the bodily synthesis of prostaglandins.
tolmetin (26171-23-3)  
Tolectin  ·  Tolmetin Sodium  ·  McN-2559
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class. It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it is marketed as Tolectin and comes as a tablet or capsule.
ketoprofen (22071-15-4)  
Orudis  ·  Benzoylhydratropic Acid  ·  RP-19583
Ketoprofen, (RS)-2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin. As of 2015 the cost for a typical month of medication in the United States is 50 to 100 USD.
flurbiprofen (5104-49-4, 51543-38-5)  
Froben  ·  Ansaid  ·  Ocufen
Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of ibuprofen.
diflunisal (22494-42-4)  
Dolobid  ·  Dolocid  ·  Novo-Diflunisal
Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. It was developed by Merck Sharp & Dohme in 1971, as MK647, after showing promise in a research project studying more potent chemical analogs of aspirin. It was first sold under the brand name Dolobid, marketed by Merck & Co., but generic versions are now widely available.
CLOBETASOL PROPIONATE (25122-46-7)  
Clobetasol  ·  Temovate  ·  Dermovate
Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available.
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