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Related to PHENFORMIN HYDROCHLORIDE, Monoamine reuptake inhibitors

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Amines (1)
Antiarrhythmic agents (1)
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Drugs acting on the nervous system (1)
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H1 receptor antagonists (1)
Muscle relaxants (1)
Norepinephrine reuptake inhibitors (1)
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Psychoactive drugs (1)
Sodium channel blockers (1)

orphenadrine (83-98-7)  
Norflex  ·  Orphenadrine Citrate  ·  Disipal
Orphenadrine (sold under many brand names worldwide) is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine. It is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs. It was discovered and developed in the 1940s.

Related Results:
Nisoxetine (53179-07-0, 57754-86-6, 57226-61-6)  
3-(o-methoxyphenoxy)-N-methyl-3-phenylpropylamine  ·  LY 135252  ·  N-methyl-gamma-(2-methylphenoxy)phenylpropanolamine
Nisoxetine, originally synthesized in the Lilly research laboratories during the early 1970s, is a potent and selective inhibitor for the reuptake of norepinephrine (noradrenaline) into synapses. It currently has no clinical applications in humans, although it was originally researched as an antidepressant. Nisoxetine is now widely used in scientific research as a standard selective norepinephrine reuptake inhibitor.
Brofaromine (63638-91-5)  
Brofaromine (proposed brand name Consonar) is a reversible inhibitor of monoamine oxidase A (RIMA) discovered by Ciba-Geigy. The compound was primarily researched in the treatment of depression and anxiety but its development was dropped before it was brought to market. Brofaromine also acts as a serotonin reuptake inhibitor, and its dual pharmacologic effects offered promise in the treatment of a wide spectrum of depressed patients while producing less severe anticholinergic side effects in comparison with older standard drugs like the tricyclic antidepressants.
pargyline (555-57-7)  
Pargyline Hydrochloride
Pargyline (brand name Eutonyl) is an irreversible selective monoamine oxidase (MAO)-B inhibitor drug (IC50 for MAO-A is 0.01152 µmol/L and for MAO-B is 0.00820 µmol/L) It was brought to market in the US and the UK by Abbott in 1963 as an antihypertensive drug branded "Eutonyl". It was one of several MAO inhibitors introduced in the 1960s including nialamide, isocarboxazid, phenelzine, and tranylcypromine. By 2007 the drug was discontinued and as of 2014 there were no generic versions available in the US.
Zimelidine dihydrochloride (60525-15-7)  
Zimelidine  ·  Zimeldine  ·  H-102-09
citalopram hydrobromide (59729-32-7)  
Citalopram (brand names: Celexa, Cipramil and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration approval to treat major depression, which it received in 1998, and is prescribed off-label for other conditions.
Milnacipran (92623-85-3, 96847-55-1)  
Milnacipran (trade names Ixel, Savella, Dalcipran, Toledomin) is a serotonin–norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. It is not approved for the clinical treatment of major depressive disorder in the USA, but it is in other countries.
Nomifensine (24526-64-5, 89664-20-0)  
Merital  ·  Nomifensine Maleate  ·  Nomifensine Maleate (1:1)
Nomifensine (Merital, Alival) is a norepinephrine-dopamine reuptake inhibitor, i.e. a drug that increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. This is a mechanism of action shared by some recreational drugs like cocaine and the medication tametraline (see DRI).
Nomifensine maleate (32795-47-4)  
Nomifensine  ·  Merital  ·  Nomifensine Maleate (1:1)
Alaproclate (60719-82-6)  
alaproclate hydrochloride, (D)-isomer  ·  A 23189  ·  alaproclate hydrochloride
Alaproclate (developmental code name GEA-654) is a drug that was being developed as an antidepressant by the Swedish pharmaceutical company Astra AB (now AstraZeneca) in the 1970s. It acts as a selective serotonin reuptake inhibitor (SSRI), and along with zimelidine and indalpine, was one of the first of its kind. Development was discontinued due to the observation of liver complications in rodent studies.
Pirlindole (60762-57-4)  
Pirlindole (Lifril, Pyrazidol) is a reversible inhibitor of monoamine oxidase A (RIMA) which was developed and is used in Russia as an antidepressant. It is structurally and pharmacologically related to metralindole.
Reboxetine (98769-81-4, 98819-76-2, 71620-89-8)  
Esreboxetine is a selective norepinephrine reuptake inhibitor which was under development by Pfizer for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. It is the (S,S)-(+)-enantiomer of reboxetine and is even more selective in comparison. However, recently it has been shown that esreboxetine could be effective in fibromyalgia patients.
Clomipramine hydrochloride (17321-77-6)  
Clomipramine  ·  Anafranil  ·  Chlorimipramine
Clomipramine, sold under the brand name Anafranil among others, is a tricyclic antidepressant (TCA). It is used for the treatment of obsessive–compulsive disorder, panic disorder, major depressive disorder, and chronic pain. It may decrease the risk of suicide in those over the age of 65.
citalopram (59729-33-8)  
Escitalopram  ·  Lexapro  ·  Cytalopram
Citalopram (brand names: Celexa, Cipramil and others) is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. It has U.S. Food and Drug Administration approval to treat major depression, which it received in 1998, and is prescribed off-label for other conditions.
Pirlindole hydrochloride (16154-78-2, 60762-57-4)  
pyrlindole  ·  pirlindole  ·  1,10-trimethylene-8-methyl-1,2,3,4-tetrahydropyrazino(1,2-a)indole
mianserin (78684-63-6, 24219-97-4)  
Mianserin Hydrochloride  ·  Org GB 94  ·  Tolvon
Mianserin, sold under the brand name Tolvon among others, is an atypical antidepressant which is used in the treatment of depression in Europe and elsewhere in the world. It is a tetracyclic antidepressant (TeCA). Mianserin is closely related to mirtazapine, both chemically and in terms of its actions and effects, although there are significant differences between the two drugs.
FLUOXETINE HYDROCHLORIDE (56296-78-7, 59333-67-4)  
Fluoxetine  ·  Prozac  ·  Sarafem
Fluoxetine, also known by trade names Prozac and Sarafem among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder (OCD), bulimia nervosa, panic disorder, and premenstrual dysphoric disorder. It may decrease the risk of suicide in those over the age of 65.
Imipraminoxide (6829-98-7)  
imipramine-N-oxide  ·  5-(3-(dimethylamino)propyl)-10,11-dihydro-5H- dibenz(b,f)azepine 5-(3-N-oxide)  ·  imipramine N-oxide hydrochloride
(Z) Fluvoxamine (54739-18-3)  
Fluvoxamine  ·  Luvox  ·  Fluvoxamine Maleate
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