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trc-canada.com, 2-Pyridones


Cyclic compounds (4)
Six-membered rings (4)
Pharmaceuticals (3)
Aromatic compounds (2)
Aromatic amines (1)
Aromatic ketones (1)
Cardiac stimulants (1)
Drugs acting on the cardiovascular system (1)
Drugs acting on the respiratory system (1)
Inotropic agents (1)
PDE3 inhibitors (1)
Pyridines (1)
Vasodilators (1)


AK Scientific (3)
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Sigma Aldrich (2)
Accela (1)
Frontier Scientific (1)
Matrix Scientific (1)

PIRFENIDONE (53179-13-8)  
Pirfenidone is a medication used for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. It was developed by several companies worldwide, including the original patent holder, Marnac, InterMune Inc.
CICLOPIROX (29342-05-0)  
Loprox  ·  ciclopirox olamine  ·  Penlac
Ciclopirox olamine is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. It is most useful against Tinea versicolor. It is sold under many brand names worldwide.
Amrinone (60719-84-8)  
Inocor  ·  Amrinone LAW Brand  ·  Cordemcura
Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR).
3,5,6-TRICHLORO-2-PYRIDINOL (6515-38-4)  
3,5,6-trichloro-2-pyridinol sodium salt
TCPy or 3,5,6-trichloro-2-pyridinol is a metabolite of chlorpyrifos and chlorpyrifos-methyl, both organophosphate insecticides. A study in Massachusetts reported a correlation between exposure to TCPy and lower testosterone levels in men. According to this source, exposure is "widespread" and of "potential public health importance".
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