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trc-canada.com, Antiasthmatic drugs

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Drugs acting on the respiratory system (7)
Respiratory agents (7)
Pharmaceuticals (6)
PDE4 inhibitors (5)
Halides (3)
Organohalides (3)
Anti-inflammatory agents (2)
Anti-inflammatory and antirheumatic products (2)
Antineoplastic and immunomodulating drugs (2)
Corticosteroid esters (2)
Drugs acting on the musculoskeletal system (2)
Drugs acting on the nervous system (2)
Glucocorticoids (2)
Hormonal agents (2)
Immunomodulating drugs (2)
Immunosuppressants (2)
Ketones (2)
Mineralocorticoids (2)
Organofluorides (2)
Psychoactive drugs (2)
Systemic hormonal preparations (2)
Xanthines (2)
Acids (1)
Carboxylic acids (1)
Consumer Ingredients (1)
Cyclic compounds (1)
Cycloalkanes (1)
Cyclopropanes (1)
Drugs acting on the cardiovascular system (1)
Nasal sprays (1)
Organic acids (1)
Organochlorides (1)
Three-membered rings (1)
Vasodilators (1)

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FLUTICASONE PROPIONATE (80474-14-2)  
Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis.
Roflumilast (162401-32-3)  
Roflumilast (trade names Daxas, Daliresp) is a drug that acts as a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). It has anti-inflammatory effects and is used as an orally administered drug for the treatment of inflammatory conditions of the lungs such as chronic obstructive pulmonary disease (COPD). In June 2010, it was approved in the EU for severe COPD associated with chronic bronchitis.
pentoxifylline (6493-05-6)  
Trental  ·  Torental  ·  Pentoxil
Pentoxifylline, also known as oxpentifylline, is a xanthine derivative used as a drug to treat muscle pain in people with peripheral artery disease. It is generic and sold under many brand names worldwide.
BECLOMETHASONE DIPROPIONATE (5534-09-8)  
Beclomethasone  ·  Vanceril  ·  Beconase
Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication. It is available as an inhaler, cream, pills, and nasal spray. The inhaled form is used in the long-term management of asthma.
luteolin (491-70-3)  
Luteoline  ·  3',4',5,7-Tetrahydroxy-Flavone  ·  3',4',5,7-Tetrahydroxyflavone
Luteolin is a flavone, a type of flavonoid, with a yellow crystalline appearance.
propentofylline (55242-55-2)  
HWA 285  ·  1-(5'-oxohexyl)-3-methyl-7-propylxanthine  ·  HWA-285
Propentofylline (HWA 285) is a xanthine derivative with purported neuroprotective effects.
Cilomilast (153259-65-5)  
Cilomilast (INN, codenamed SB-207,499, proposed trade name Ariflo) is a drug which was developed for the treatment of respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). It is orally active and acts as a selective phosphodiesterase-4 inhibitor. Phosphodiesterase (PDE) inhibitors, such as theophylline, have been used to treat COPD for centuries; however, the clinical benefits of these agents have never been shown to outweigh the risks of their numerous adverse effects.

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azelastine (58581-89-8)  
Astelin  ·  Optivar  ·  azelastine hydrochloride
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
AZELASTINE HYDROCHLORIDE (79307-93-0, 37932-96-0)  
azelastine  ·  Astelin  ·  Optivar
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used as a first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Azelastine has been formulated both as a nasal spray and as eye drops and are available worldwide under many brand names.
AMBUPHYLLINE (5634-34-4)  
bufylline  ·  theophylline aminoisobutanol
Ambuphylline (or bufylline) is a combination of theophylline and aminoisobutanol used as a bronchodilator. It also acts and may be used as a diuretic.
cromolyn (16110-51-3)  
Cromolyn Sodium  ·  Cromoglycate  ·  Intal
Cromoglicic acid (INN) (also referred to as cromolyn (USAN), cromoglycate (former BAN), or cromoglicate) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma.
mequitazine (147780-50-5, 29216-28-2)  
Mircol  ·  Primalan  ·  mequitazine hydrochloride
Mequitazine (trade name Primalan) is an H1 antagonist and anticholinergic of the phenothiazine chemical class. It is used to treat allergies and rhinitis.
terfenadine (50679-08-8)  
Seldane  ·  Terfenidine  ·  Sigma Tau Brand of Terfenadine
Terfenadine is an antihistamine formerly used for the treatment of allergic conditions. It was brought to market by Hoechst Marion Roussel (now Sanofi-Aventis) and was marketed under various brand names, including Seldane in the United States, Triludan in the United Kingdom, and Teldane in Australia. It was superseded by fexofenadine in the 1990s due to the risk of a particular type of disruption of the electrical rhythms of the heart (specifically cardiac arrhythmia caused by QT interval prolongation) and has been withdrawn from markets worldwide.
KETOTIFEN FUMARATE (34580-14-8)  
Ketotifen  ·  Zaditen  ·  Ketotiphen
Ketotifen, sold under the brand name Zaditor among others, is a first-generation noncompetitive H1-antihistamine and mast cell stabilizer. It is most commonly sold as a salt with fumaric acid, ketotifen fumarate, and is available in two forms. In its ophthalmic form, it is used to treat allergic conjunctivitis.
nimesulide (51803-78-2)  
Aulin  ·  Nexen  ·  R 805
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.
loratadine (79794-75-5)  
Claritin  ·  Alavert  ·  Clarium
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives. It is also available in combination with pseudoephedrine, a decongestant, known as loratadine/pseudoephedrine.
astemizole (68844-77-9)  
Hismanal  ·  Romadin  ·  Elfar Brand of Astemizole
Astemizole (marketed under the brand name Hismanal, developmental code R43512) was a second-generation antihistamine drug that has a long duration of action. Astemizole was discovered by Janssen Pharmaceutica in 1977. It has been withdrawn from the market in most countries because of rare but potentially fatal side effects (QTc interval prolongation and related arrhythmias due to hERG channel blockade).
Xanthinol (2530-97-4)  
Xanthinol is a drug prepared from theophylline used as a vasodilator. It is most often used as the salt with niacin (nicotinic acid), known as xantinol nicotinate.
loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
chlorpheniramine (113-92-8, 32188-09-3, 132-22-9)  
Chlorpheniramine Maleate  ·  Teldrin  ·  Piriton
Chlorphenamine (also known as chlorpheniramine, CP, or CPM) is a first-generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first-generation antihistamines. Chlorphenamine is one of the most commonly used antihistamines in small-animal veterinary practice.
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