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trc-canada.com, Bisphosphonates

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Osteoporosis drugs (5)
Pharmaceuticals (5)
Systemic hormonal preparations (5)
Amines (1)
Bases (chemistry) (1)
Chelating agents (1)
Consumer Ingredients (1)
Drugs acting on the musculoskeletal system (1)
Food Additives (1)
Musculoskeletal system drug (1)

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AK Scientific (4)
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alendronate (66376-36-1)  
Fosamax  ·  Alendronate Sodium  ·  4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate
Alendronic acid (INN) or alendronate sodium — sold as Fosamax by Merck — is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. It is marketed alone as well as in combination with vitamin D (2,800 IU and 5,600 IU, under the name Fosamax+D). Merck's U.S.
Ibandronic Acid (114084-78-5)  
Ibandronic acid (INN) or ibandronate sodium (USAN) is a potent bisphosphonate drug developed by Hoffman La Roche and used in the prevention and treatment of osteoporosis and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat hypercalcemia (elevated blood calcium levels).
Etidronic acid (7414-83-7, 2809-21-4, 66052-91-3)  
Etidronate  ·  EHDP  ·  HEDP
Etidronic acid (INN) or 1-hydroxyethane 1,1-diphosphonic acid (HEDP) is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment. An etidronate is a salt of etidronic acid, abbreviated MnHEDP (M: is a cation, n: number of M maximum 4).
PAMIDRONIC ACID (40391-99-9, 57248-88-1)  
APD  ·  pamidronate  ·  Aredia
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate (marketed as Aredia by Novartis and as Pamimed by Curacell Biotech), is a nitrogen-containing bisphosphonate used to prevent osteoporosis.
Methylenediphosphonic acid (1984-15-2, 63347-66-0)  
methylene diphosphonate  ·  methylene diphosphonate, tetrasodium salt, (32)P-labeled  ·  disodium methanediphosphonate
Medronic acid (conjugate base, medronate), also known as methylene diphosphonate, is the smallest bisphosphonate. Its complex with radioactive technetium, 99mTc medronic acid, is used in nuclear medicine to detect bone abnormalities, including metastases.

Related Results:
alendronate (66376-36-1)  
Fosamax  ·  Alendronate Sodium  ·  4-Amino-1-Hydroxybutylidene 1,1-Biphosphonate
Alendronic acid (INN) or alendronate sodium — sold as Fosamax by Merck — is a bisphosphonate drug used for osteoporosis, osteogenesis imperfecta, and several other bone diseases. It is marketed alone as well as in combination with vitamin D (2,800 IU and 5,600 IU, under the name Fosamax+D). Merck's U.S.
CLODRONATE DISODIUM (88416-50-6, 22560-50-5)  
Clodronate  ·  Dichloromethylene Diphosphonate  ·  Dichloromethane Diphosphonate
PAMIDRONIC ACID (40391-99-9, 57248-88-1)  
APD  ·  pamidronate  ·  Aredia
Pamidronic acid (INN) or pamidronate disodium (USAN), pamidronate disodium pentahydrate (marketed as Aredia by Novartis and as Pamimed by Curacell Biotech), is a nitrogen-containing bisphosphonate used to prevent osteoporosis.
PAMIDRONATE DISODIUM (57248-88-1)  
APD  ·  pamidronate  ·  Aredia
Zoledronic acid (118072-93-8)  
Zoledronic acid, also known as zoledronate, is a medication used to treat a number of bone diseases. This include osteoporosis, high blood calcium due to cancer, bone breakdown due to cancer, and Paget’s disease of bone. It is given by injection into a vein.
Risedronate (105462-24-6, 115436-72-1)  
Risedronic acid (INN) often used as its sodium salt risedronate sodium (USAN) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone. It is produced and marketed by Warner Chilcott, Sanofi-Aventis, and in Japan by Takeda under the trade names Actonel, Atelvia, and Benet. It is also available in a preparation that includes a calcium carbonate supplement, as Actonel with Calcium.
Clodronic Acid (10596-23-3)  
Clodronate  ·  Dichloromethylene Diphosphonate  ·  Clodronate Disodium
Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-α. While bisphosphonates are shown to be effective in reducing vertebral fractures and pain, their role in improving overall survival remains unclear.
Aredia (57248-88-1, 109552-15-0)  
APD  ·  pamidronate  ·  pamidronate disodium
ipriflavone (35212-22-7)  
Osteoquine  ·  Quinogin  ·  Yambolap
Ipriflavone (INN) (brand name Yambolap) is a synthetic isoflavone which may be used to inhibit bone resorption, maintain bone density and to prevent osteoporosis in postmenopausal women. It is not used to treat osteoporosis. It slows down the action of the osteoclasts (bone-eroding cells), possibly allowing the osteoblasts (bone-building cells) to build up bone mass.
Alphacalcidol (41294-56-8)  
alfacalcidol  ·  1-alpha-oxycholecalciferol  ·  1-hydroxycholecalciferol, aluminum salt
alfacalcidol (41294-56-8)  
1-alpha-oxycholecalciferol  ·  1-hydroxycholecalciferol, aluminum salt  ·  1-hydroxycholecalciferol, (1beta,3beta-(5E,7E))-isomer
raloxifene (84449-90-1)  
Raloxifene, sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer. It is taken by mouth. Side effects of raloxifene include hot flashes, leg cramps, and an increased risk of blood clots and other cardiovascular events such as stroke.
Etidronic acid (7414-83-7, 2809-21-4, 66052-91-3)  
Etidronate  ·  EHDP  ·  HEDP
Etidronic acid (INN) or 1-hydroxyethane 1,1-diphosphonic acid (HEDP) is a bisphosphonate used in detergents, water treatment, cosmetics and pharmaceutical treatment. An etidronate is a salt of etidronic acid, abbreviated MnHEDP (M: is a cation, n: number of M maximum 4).
DEFLAZACORT (14484-47-0)  
Zamene  ·  Dezacor  ·  Calcort
Deflazacort (trade name Emflaza or Calcort among others) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.
Disodium clodronate (22560-50-5)  
Clodronate  ·  Dichloromethylene Diphosphonate  ·  Clodronate Disodium
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