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trc-canada.com, Neurotoxins

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quinolinic acid (89-00-9)  
Quinolinate  ·  Quinolinic Acid, Disodium Salt  ·  Quinolinic Acid, Strontium Salt
Quinolinic acid (abbreviated QUIN or QA), also known as pyridine-2,3-dicarboxylic acid, is a dicarboxylic acid with a pyridine backbone. It is a colorless solid. It is the biosynthetic precursor to nicotine.
diisopropyl fluorophosphate (55-91-4)  
DFP  ·  Isoflurophate  ·  Diisopropylfluorophosphate
Diisopropyl fluorophosphate is an oily, colorless liquid with the chemical formula C6H14FO3P. It is used in medicine and as an organophosphorus insecticide. It is stable, but undergoes hydrolysis when subjected to moisture, producing hydrofluoric acid.
15920-93-1 (15920-93-1)  
β-Methylamino-L-alanine, or BMAA, is a non-proteinogenic amino acid produced by cyanobacteria. BMAA is a neurotoxin and its potential role in various neurodegenerative disorders is the subject of scientific research.
Myosmine (532-12-7)  
Myosmine is an alkaloid found in tobacco and other plants. Chemically, it is closely related to nicotine.
Quisqualate (52809-07-1)  
Quisqualic acid is an agonist of the AMPA, kainate, and group I metabotropic glutamate receptors. It is one of the most potent AMPA receptor agonists known. It causes excitotoxicity and is used in neuroscience to selectively destroy neurons in the brain or spinal cord.
Anabaseine (3471-05-4)  
Anabaseine (3,4,5,6-Tetrahydro-2,3’-bipyridine) is an alkaloid toxin produced by Nemertines and Aphaenogaster ants. It is structurally similar to nicotine and anabasine. Similarly, it has been shown to act as an agonist on most nicotinic acetylcholine receptors in the central nervous system and peripheral nervous system.

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T2 Toxin (21259-20-1)  
Fusaritoxin  ·  Fusariotoxin  ·  T 2 Toxin
T-2 Mycotoxin (pronounced as 'Tee-Two') is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and animals.
ZEARALENONE (17924-92-4, 36455-70-6)  
F2 Toxin  ·  F-2 Toxin  ·  F 2 Toxin
Zearalenone (ZEN), also known as RAL and F-2 mycotoxin, is a potent estrogenic metabolite produced by some Fusarium and Gibberella species. Particularly, is produced by Fusarium graminearum, Fusarium culmorum, Fusarium cerealis, Fusarium equiseti, Fusarium verticillioides, and Fusarium incarnatum. Several Fusarium species produce toxic substances of considerable concern to livestock and poultry producers, namely deoxynivalenol, T-2 toxin, HT-2 toxin, diacetoxyscirpenol (DAS) and zearalenone.
TETRODOTOXIN (4368-28-9)  
Tarichatoxin  ·  Tetradotoxin  ·  Fugu Toxin
Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other aquatic animals (e.g., in blue-ringed octopuses, rough-skinned newts, and moon snails), it is actually produced by certain infecting or symbiotic bacteria like Pseudoalteromonas, Pseudomonas, and Vibrio as well as other species found in the animals.
Tarichatoxin (4368-28-9)  
Tetrodotoxin (TTX) is a potent neurotoxin. Its name derives from Tetraodontiformes, an order that includes pufferfish, porcupinefish, ocean sunfish, and triggerfish; several of these species carry the toxin. Although tetrodotoxin was discovered in these fish and found in several other aquatic animals (e.g., in blue-ringed octopuses, rough-skinned newts, and moon snails), it is actually produced by certain infecting or symbiotic bacteria like Pseudoalteromonas, Pseudomonas, and Vibrio as well as other species found in the animals.
SAXITOXIN (73603-72-2, 35523-89-8)  
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the human illness known as paralytic shellfish poisoning (PSP). The term saxitoxin originates from the genus name of the butter clam (Saxidomus) from which it was first isolated.
DSP 4 (62078-98-2)  
DSP4  ·  az-DSP 4  ·  DSP-4
For the Super NES enhancement chip see List of Super NES enhancement chips DSP-4, or N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine, is a neurotoxin selective for noradrenergic neurons, capable of crossing the blood–brain barrier. It exerts transient effects in peripheral sympathetic neurons, but more permanent changes within neurons of the central nervous system. It can induce long-term depletion in cortical and spinal levels of noradrenaline.
Melitten (37231-28-0)  
Melittin  ·  Mellitin
1,2-Dibromotetrafluorobenzene (827-08-7)  
diphtheria toxin fragment B  ·  DTFB  ·  fragment B diphtheria toxin
veratridine (71-62-5)  
Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a neurotoxin by preventing the inactivation of sodium ion channels. It is primarily obtained from plants of the genuses Veratrum and Schoenocaulon. It binds to intramembrane receptor site 2 and increases intracellular Ca2+ concentration.
HC Toxin (83209-65-8)  
cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine)  ·  HC-toxin  ·  Helminthosporium carbonum toxin
DIQUAT (85-00-7, 2764-72-9, 231-36-7)  
Diquat Dibromide
Diquat is a contact herbicide that produces desiccation and defoliation most often available as the dibromide, diquat dibromide. Brand names for this formulation include Aquacide, Dextrone, Preeglone, Deiquat, Spectracide, Detrone, Reglone, Reglon, Reglox, Tribune, Ortho-Diquat, Weedtrine-D, Weedol 2 and, in combination with glyphosate, Resolva. Diquat is a non-selective herbicide that acts quickly to damage only those parts of the plant to which it is applied.
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