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www.sigmaaldrich.com, Anti-inflammatory agents, Antineoplastic and immunomodulating drug

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Anti-inflammatory and antirheumatic products (26)
Antineoplastic and immunomodulating drugs (26)
Drugs acting on the musculoskeletal system (26)
Glucocorticoids (23)
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Cyclic compounds (6)
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dexamethasone (23495-06-9, 26628-22-8, 50-02-2)  
Hexadrol  ·  Dexasone  ·  Maxidex
Dexamethasone is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis. In adrenocortical insufficiency, it should be used together with a medication that has greater mineralocorticoid effects such as fludrocortisone.
Prednisolone (50-24-8)  
Predate  ·  Predonine  ·  DiAdresonF
Prednisolone is a steroid medication used to treat certain types of allergies, inflammatory conditions, autoimmune disorders, and cancers. Some of these conditions include adrenocortical insufficiency, high blood calcium, rheumatoid arthritis, dermatitis, eye inflammation, asthma, and multiple sclerosis. It is used by mouth, injection into a vein, as a skin cream, and as eye drops.
prednisone (53-03-2)  
Prednisone is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug. It is used to treat certain inflammatory diseases (such as moderate allergic reactions), some autoimmune diseases, and (at higher doses) some types of cancer, but it has significant adverse effects.
progesterone (57-83-0)  
Pregnenedione  ·  Progesterone, (13 alpha,17 alpha)-(+-)-Isomer  ·  Progesterone, (9 beta,10 alpha)-Isomer
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone has a variety of important functions in the body.
methylprednisolone (83-43-2, 6923-42-8)  
Medrol  ·  Metipred  ·  Urbason
Methylprednisolone, sold under the brand names Depo-Medrol and Solu-Medrol among others, is a corticosteroid medication used to suppress the immune system and decrease inflammation. Conditions in which it is used include skin diseases, rheumatic disorders, allergies, asthma, croup, COPD, certain cancers, multiple sclerosis, and as add-on therapy for tuberculosis. It is given by mouth or by injection into a vein, or muscle.
triamcinolone (51855-44-8, 124-94-7)  
Aristocort  ·  Volon
Triamcinolone is an intermediate-acting synthetic glucocorticoid given orally, by injection, by inhalation, or as a topical ointment or cream.
hydrocortisone (50-23-7)  
Cortisol  ·  Cortril  ·  Epicortisol
Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication. Uses include conditions such as adrenocortical insufficiency, adrenogenital syndrome, high blood calcium, thyroiditis, rheumatoid arthritis, dermatitis, asthma, and COPD. It is the treatment of choice for adrenocortical insufficiency.
celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
betamethasone (24024-03-1, 378-44-9)  
Celestone  ·  Flubenisolone  ·  Betadexamethasone
Betamethasone is a steroid medication. It is used for a number of diseases including rheumatic disorders such as rheumatoid arthritis and systemic lupus erythematosus, skin diseases such as dermatitis and psoriasis, allergic conditions such as asthma and angioedema, preterm labor to speed the development of the baby's lungs, Crohn's disease, cancers such as leukemia, and along with fludrocortisone for adrenocortical insufficiency, among others. It can be taken by mouth, injected into a muscle, or applied as a cream.
FLUOCINOLONE ACETONIDE (67-73-2)  
Capex  ·  Synalar  ·  Jellin
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity.
CLOBETASOL PROPIONATE (25122-46-7)  
Clobetasol  ·  Temovate  ·  Dermovate
Clobetasol propionate is a corticosteroid of the glucocorticoid class used to treat various skin disorders including eczema and psoriasis. It is also highly effective for contact dermatitis caused by exposure to poison ivy/oak. Clobetasol belongs to US Class I (Europe: class IV) of the corticosteroids, making it one of the most potent available.
hydroxyprogesterone (604-09-1, 68-96-2)  
17 Hydroxyprogesterone  ·  17 alpha Hydroxyprogesterone  ·  17 alpha-Hydroxyprogesterone
Hydroxyprogesterone (OHP) may refer to: 3α-Hydroxyprogesterone (3α-dihydroprogesterone) 3β-Hydroxyprogesterone (3β-dihydroprogesterone) 11α-Hydroxyprogesterone 11β-Hydroxyprogesterone (21-deoxycorticosterone) 16α-Hydroxyprogesterone 17α-Hydroxyprogesterone 20α-Hydroxyprogesterone 21-Hydroxyprogesterone (11-deoxycorticosterone)
fluocinonide (356-12-7)  
Lidex  ·  Topsyn  ·  Lidemol
Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. The usual prescription concentration is 0.05% as a topical cream, ointment, solution, or gel.
BECLOMETHASONE DIPROPIONATE (5534-09-8)  
Beclomethasone  ·  Vanceril  ·  Beconase
Beclometasone dipropionate, also spelled beclomethasone dipropionate and sold under the brand name Qvar among others, is a steroid medication. It is available as an inhaler, cream, pills, and nasal spray. The inhaled form is used in the long-term management of asthma.
DESONIDE (638-94-8)  
Tridesilon  ·  Desowen  ·  Desocort
Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam.
fluorometholone (426-13-1)  
FML  ·  FML Forte  ·  FML Liquifilm
Fluorometholone (INN, BAN, JAN) (brand names Efflumidex, Flucon, FML Forte, FML, others), also known as 6α-methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, is a synthetic glucocorticoid which is used in the treatment of inflammatory eye diseases. The C17α acetate ester, fluorometholone acetate (brand name Flarex), is also a glucocorticoid and is used for similar indications. Specifically, it is indicated for use in the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.
amcinonide (51022-69-6)  
Cyclocort  ·  Hermal brand of amcinonide  ·  Amciderm
Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis. Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity.
Hydrocortisone 17-butyrate (13609-67-1, 135467-84-4)  
Locoid  ·  hydrocortisone butyrate  ·  cortisol 17-butyrate
Hydrocortisone 17-butyrate is a form of hydrocortisone butyrate.
medrysone (2668-66-8)  
HMS Liquifilm  ·  HMS suspension  ·  11-hydroxy-6-methylprogesterone
Medrysone (INN, USAN) (brand names HMS, Medrocort, others; former developmental code name NSC-63278), also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases. It has been discontinued in the United States. Although it is very similar in structure to progesterone, neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone.
halcinonide (3093-35-4)  
Halog  ·  Halciderm  ·  SQ 18,566
Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification. It is used topically (in a 0.05% cream provided as Halog) in the treatment of certain skin conditions.
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