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www.sigmaaldrich.com, Anti-inflammatory agents, Aromatic compounds

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Anti-inflammatory and antirheumatic products (19)
Cyclic compounds (19)
Drugs acting on the musculoskeletal system (19)
Analgesics (15)
Antipyretics (15)
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Nonsteroidal anti-inflammatory drugs (15)
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Diclofenac (15307-86-5)  
Voltaren  ·  Diclofenac Sodium  ·  SR 38
Diclofenac (sold under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. It is supplied as or contained in medications under a variety of trade names. The name "diclofenac" derives from its chemical name: 2-(2,6-dichloranilino) phenylacetic acid.
ketorolac (66635-83-4, 74103-06-3)  
Ketorolac, sold under the brand name Toradol among others, is a nonsteroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives, used as an analgesic. It is considered a first-generation NSAID. Ketorolac acts by inhibiting the bodily synthesis of prostaglandins.
tolmetin (26171-23-3)  
Tolectin  ·  Tolmetin Sodium  ·  McN-2559
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class. It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it is marketed as Tolectin and comes as a tablet or capsule.
FLUOCINOLONE ACETONIDE (67-73-2)  
Capex  ·  Synalar  ·  Jellin
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity.
flurbiprofen (5104-49-4, 51543-38-5)  
Froben  ·  Ansaid  ·  Ocufen
Flurbiprofen is a member of the phenylalkanoic acid derivative family of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Side effects are analogous to those of ibuprofen.
diflunisal (22494-42-4)  
Dolobid  ·  Dolocid  ·  Novo-Diflunisal
Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity. It was developed by Merck Sharp & Dohme in 1971, as MK647, after showing promise in a research project studying more potent chemical analogs of aspirin. It was first sold under the brand name Dolobid, marketed by Merck & Co., but generic versions are now widely available.
sulindac (32004-68-5, 9000-14-0, 38194-50-2, 49627-22-7)  
Copal  ·  Clinoril  ·  Chibret
fluocinonide (356-12-7)  
Lidex  ·  Topsyn  ·  Lidemol
Fluocinonide (Fluonex, Lidex, Lidex-E, Lonide, Lyderm, and Vanos) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. The usual prescription concentration is 0.05% as a topical cream, ointment, solution, or gel.
amcinonide (51022-69-6)  
Cyclocort  ·  Hermal brand of amcinonide  ·  Amciderm
Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis. Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity.
nimesulide (51803-78-2)  
Aulin  ·  Nexen  ·  R 805
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.
halcinonide (3093-35-4)  
Halog  ·  Halciderm  ·  SQ 18,566
Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification. It is used topically (in a 0.05% cream provided as Halog) in the treatment of certain skin conditions.
tiaprofenic acid (103667-49-8, 33005-95-7)  
Surgam  ·  Nu-Tiaprofenic  ·  tiaprofenic acid, calcium salt
Tiaprofenic acid is a nonsteroidal anti-inflammatory drug (NSAID) of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain. The typical adult dose is 300 mg twice daily. It is not recommended in children.
Aceclofenac (89796-99-6)  
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It should not be given to people with porphyria or breast-feeding mothers, and is not recommended for children.
Tarenflurbil (51543-40-9)  
flurizan  ·  MPC-7869  ·  MPC7869
Tarenflurbil, Flurizan or R-flurbiprofen, is the single enantiomer of the racemate NSAID flurbiprofen. For several years, research and trials for the drug were conducted by Myriad Genetics, to investigate its potential as a treatment for Alzheimer's disease; that investigation concluded in June 2008 when the company announced it would discontinue development of the compound.
alclofenac (22131-79-9)  
Mervan  ·  4-allyloxy-3-chlorophenylacetic acid  ·  Prinalgin
Alclofenac is a nonsteroidal anti-inflammatory drug (NSAID).
FLUNIXIN (38677-85-9)  
Flunixin is a nonsteroidal anti-inflammatory drug (NSAID), analgesic, and antipyretic used in horses, cattle and pigs. It is often formulated as the meglumine salt. In the United States, it is regulated by the U.S.
CLONIXIN (17737-65-4)  
CBA-93626  ·  CBA93626  ·  CBA 93626
Clonixin is a nonsteroidal anti-inflammatory drug (NSAID). It also has analgesic, antipyretic, and platelet-inhibitory actions. It is used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
Fenclozic acid (17969-20-9)  
Fenclozic acid is an analgesic, antipyretic, and anti-inflammatory drug. It has been withdrawn in 1970 due to jaundice.

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