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www.sigmaaldrich.com, Anti-inflammatory agents, COX-2 inhibitors

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Analgesics (5)
Anti-inflammatory and antirheumatic products (5)
Antipyretics (5)
Drugs acting on the musculoskeletal system (5)
Drugs acting on the nervous system (5)
Nonsteroidal anti-inflammatory drugs (5)
Cyclic compounds (4)
Pharmaceuticals (4)
Five-membered rings (3)
Isoxazoles (2)
Alkaloids (1)
Antineoplastic and immunomodulating drugs (1)
Antineoplastic drugs (1)
Pyrazoles (1)
Pyridines (1)
Six-membered rings (1)

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AK Scientific (4)
Matrix Scientific (3)
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Oakwood Chemical (1)

celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
Valdecoxib (181695-72-7)  
Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. Valdecoxib was manufactured and marketed under the brand name Bextra by G.
Etoricoxib (202409-33-4)  
Etoricoxib (Arcoxia) is a selective COX-2 inhibitor from Merck & Co. Currently it is approved in more than 80 countries worldwide but not in the US, where the Food and Drug Administration (FDA) has required additional safety and efficacy data for etoricoxib before it will issue approval.
Parecoxib (198470-84-7)  
Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
Rutaecarpine (84-26-4)  
Rutecarpine or rutaecarpine is a COX-2 inhibitor isolated from Euodia ruticarpa.

Related Results:
celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)  
brobenzoxaldine, broxyquinoline drug combination  ·  Intestopan  ·  Enteroquin
nimesulide (51803-78-2)  
Aulin  ·  Nexen  ·  R 805
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.
Andrographolide (5508-58-7)  
isoandrographolide  ·  17-hydro-9-dehydro-andrographolide
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke.
parthenolide (20554-84-1)  
parthenolide, (1aR-(1aR*,4E,7aS*,10aS*,10bR*))-isomer
Parthenolide is a sesquiterpene lactone of the germacranolide class which occurs naturally in the plant feverfew (Tanacetum parthenium), after which it is named. It is found in highest concentration in the flowers and fruit.
4-Hydroxyquinazoline (491-36-1)  
4(3H)-quinazolinone  ·  quinazolin-4-one
EMBELIN (550-24-3)  
2,5-dihydroxy-3-undecyl-1,4-benzoquinone  ·  potassium embelate
quinazolin-4-ylamine (15018-66-3)  
4-quinazolinamine  ·  15018-66-3
5-Bromo-4'-chlorosalicylanilide (3679-64-9)  
5-bromosalicyl-4'-chloranilide  ·  salifungin
Bromochlorosalicylanilide is an antifungal. It may cause allergic contact dermatitis in some individuals.
QUINAZOLINE (253-82-7)  
Quinazoline is a organic compound with the formula C8H6N2. It is an aromatic heterocycle with a bicyclic structure consisting of two fused six-membered aromatic rings, a benzene ring and a pyrimidine ring. It is a light yellow crystalline solid that is soluble in water.
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