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www.sigmaaldrich.com, Anti-inflammatory agents, Drugs acting on the cardiovascular system, Aromatic compounds, Dermatologic drugs, Systemic hormonal preparations, Acetonides

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FLUOCINOLONE ACETONIDE (67-73-2)  
Capex  ·  Synalar  ·  Jellin
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity.

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thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)  
brobenzoxaldine, broxyquinoline drug combination  ·  Intestopan  ·  Enteroquin
4-(Trifluoromethyl)aniline (455-14-1)  
4-trifluoromethylaniline  ·  para-trifluoromethylaniline
colchicine (64-86-8)  
Colchicine, (+-)-Isomer  ·  Colchicine, (R)-Isomer
Colchicine is a medication most commonly used to treat gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as "meadow saffron"). Adverse effects are primarily gastrointestinal upset at high doses.
hydroxychloroquine (118-42-3)  
Plaquenil  ·  Hydroxychloroquine Sulfate  ·  Oxychloroquine
Hydroxychloroquine (HCQ), sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda.
loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
Melatonin (8041-44-9, 73-31-4)  
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
PHENOTHIAZINE (92-84-2)  
phenosan
Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds. Although the parent compound has no uses, derivatives of phenothiazine are highly bioactive and have widespread use and rich history. The derivative chlorpromazine revolutionized the field of psychiatry and allergy treatment.
121-30-2 (121-30-2)  
2-ACBDS  ·  2-amino-4-chloro-m-benzenedisulfonamide  ·  4-amino-6-chloro-1,3-benzenedisulfonamide
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
3-Aminophenol (591-27-5)  
3-aminophenol sulfate  ·  3-aminophenol acetate  ·  3-aminophenol hydrochloride
3-Aminophenol is an organic compound with formula C6H4(NH2)(OH). It is an aromatic amine and aromatic alcohol. It is the meta isomer of 2-aminophenol and 4-aminophenol.
16673-34-0 (16673-34-0)  
5-chloro-2-methoxy-N-(2-(4-sulfamoylphenyl)ethyl)benzamide
CARBAZOLE (86-74-8)  
9H-carbazole  ·  9-azafluorene  ·  dibenzo(b,d)pyrrole
Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene rings fused on either side of a five-membered nitrogen-containing ring. The compound's structure is based on the indole structure, but in which a second benzene ring is fused onto the five-membered ring at the 2–3 position of indole (equivalent to the 9a–4a double bond in carbazole, respectively).
SALICYLANILIDE (87-17-2)  
salicylanilide, sodium salt  ·  salicylanilide, zinc salt
Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide. Derivatives of salicylanilide have a variety of pharmacological uses.
Pholedrine (370-14-9)  
veritol  ·  pholedrine, sulfate (2:1), (+-)-isomer  ·  pholedrine, sulfate (1:1), (+-)-isomer
Pholedrine (Paredrinol, Pulsotyl, Veritol), also known as 4-hydroxy-N-methylamphetamine (4-HMA), 4-hydroxymethamphetamine, and para-hydroxymethamphetamine, is a drug that stimulates the sympathetic nervous system. It is administered as a topical eye drop form for the purpose of dilating the pupil and can be used to diagnose Horner's syndrome.
2-HYDROXYPYRIDINE (72762-00-6, 37342-64-6, 142-08-5)  
2-pyridinone  ·  2-pyridone  ·  2-hydroxypyridine sodium salt
2-Pyridone is an organic compound with the formula C 5H 4NH(O). It is a colourless solid. It is well known to form hydrogen bonded dimers and it is also a classic case of a compound that exists as tautomers.
coumarin (91-64-5)  
1,2-benzopyrone  ·  5,6-benzo-alpha-pyrone
Coumarin (; 2H-chromen-2-one) is a fragrant organic chemical compound in the benzopyrone chemical class, although it may also be seen as a subclass of lactones. It is a natural substance found in many plants, and a colorless crystalline substance in its standard state. The name comes from a French term for the tonka bean, coumarou, one of the sources from which coumarin was first isolated as a natural product in 1820.
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