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www.sigmaaldrich.com, Anti-inflammatory agents, Drugs acting on the cardiovascular system, Aromatic compounds, Hormonal agents, Anti-inflammatory and antirheumatic products, Dermatologic drugs

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FLUOCINOLONE ACETONIDE (67-73-2)  
Capex  ·  Synalar  ·  Jellin
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity.

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thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)  
brobenzoxaldine, broxyquinoline drug combination  ·  Intestopan  ·  Enteroquin
colchicine (64-86-8)  
Colchicine, (+-)-Isomer  ·  Colchicine, (R)-Isomer
Colchicine is a medication most commonly used to treat gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as "meadow saffron"). Adverse effects are primarily gastrointestinal upset at high doses.
hydroxychloroquine (118-42-3)  
Plaquenil  ·  Hydroxychloroquine Sulfate  ·  Oxychloroquine
Hydroxychloroquine (HCQ), sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda.
oxaprozin (21256-18-8)  
Daypro  ·  Rhoxal-oxaprozin  ·  Apo-Oxaprozin
Oxaprozin, also known as Oxaprozinum, (sold under the names: Daypro, Dayrun, Duraprox) is a nonsteroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically, it is a propionic acid derivative. It is available in 600 mg tablets.
4-(Trifluoromethyl)aniline (455-14-1)  
4-trifluoromethylaniline  ·  para-trifluoromethylaniline
azathioprine (446-86-6)  
Imuran  ·  Azothioprine  ·  Azathioprine Sodium
Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication. It is used in rheumatoid arthritis, Crohn's disease, ulcerative colitis, and in kidney transplants to prevent rejection. It is taken by mouth or injected into a vein.
loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
PHENOTHIAZINE (92-84-2)  
phenosan
Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds. Although the parent compound has no uses, derivatives of phenothiazine are highly bioactive and have widespread use and rich history. The derivative chlorpromazine revolutionized the field of psychiatry and allergy treatment.
primidone (125-33-7)  
Mysoline  ·  Sertan  ·  AstraZeneca Brand of Primidone
Primidone (INN, BAN, USP) is an anticonvulsant of the barbiturate class. It is a structural analog of phenobarbital and related to barbiturate-derivative anticonvulsants. The active metabolites, phenobarbital, p-hydroxyphenobarbital, and phenylethylmalonamide, are also anticonvulsants.
nimesulide (51803-78-2)  
Aulin  ·  Nexen  ·  R 805
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.
celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
NITAZOXANIDE (55981-09-4)  
NTZ  ·  Daxon  ·  Alinia
Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths; emerging evidence suggests that it possesses efficacy in treating a number of viral infections as well.
5-Bromo-4'-chlorosalicylanilide (3679-64-9)  
5-bromosalicyl-4'-chloranilide  ·  salifungin
Bromochlorosalicylanilide is an antifungal. It may cause allergic contact dermatitis in some individuals.
Thiocolchicine (2730-71-4)  
thiocholchicine
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