Cyclic compounds (7)
COX-2 inhibitors (3)
Aromatic ketones (2)
AK Scientific (3)
Oakwood Chemical (3)
TCI Chemicals (2)
Celebrex · SC58635 · SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. Valdecoxib was manufactured and marketed under the brand name Bextra by G.
Tolectin · Tolmetin Sodium · McN-2559
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) of the heterocyclic acetic acid derivative class. It is used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis. In the United States it is marketed as Tolectin and comes as a tablet or capsule.
Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
tiaprofenic acid (103667-49-8, 33005-95-7)
Surgam · Nu-Tiaprofenic · tiaprofenic acid, calcium salt
Tiaprofenic acid is a nonsteroidal anti-inflammatory drug (NSAID) of the arylpropionic acid (profen) class, used to treat pain, especially arthritic pain. The typical adult dose is 300 mg twice daily. It is not recommended in children.
Amtolmetin guacil (87344-06-7)
Amtolmetin guacil is a NSAID which is a prodrug of tolmetin sodium.
Fenclozic acid (17969-20-9)
Fenclozic acid is an analgesic, antipyretic, and anti-inflammatory drug. It has been withdrawn in 1970 due to jaundice.
Thalomid · Celgene Brand of Thalidomide · Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
Compound VII (98033-68-2)
WIN 53338 · WIN-53338 · WIN53338
xanthen-9-one · 9-Oxoxanthene
Xanthone is an organic compound with the molecular formula C13H8O2. It can be prepared by the heating of phenyl salicylate. In 1939, xanthone was introduced as an insecticide and it currently finds uses as ovicide for codling moth eggs and as a larvicide.
7-chloro-1H-indole-2,3-dione · 7477-63-6
Eugenin is a chromone derivative, a phenolic compound found in cloves. It is also one of the compounds responsible for bitterness in carrots.
Cryptolepine is an antimalarial drug with cytotoxic properties. It is used as an anticancer drug as it is able to intercalate into DNA at the cytosine-cytosine sites.
isoandrographolide · 17-hydro-9-dehydro-andrographolide
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke.