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www.sigmaaldrich.com, Anti-inflammatory agents, Probiotics

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Anti-inflammatory and antirheumatic products (1)
Aromatic bases (1)
Bases (chemistry) (1)
Cyclic compounds (1)
Drugs acting on the gastrointestinal system and metabolism (1)
Drugs acting on the musculoskeletal system (1)
Fermented soy-based foods (1)
Food Additives (1)
Heterocyclic compound (1)
Heterocyclic compounds (1)
Probiotic Foods (1)
Pyrazines (1)
Six-membered rings (1)

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2,3,5,6-Tetramethylpyrazine (1124-11-4)  
tetramethylpyrazine  ·  Liqustrazine  ·  chuanxiongzine
Tetramethylpyrazine, also known as ligustrazine, is a chemical compound found in natto and in fermented cocoa beans. When purified, tetramethylpyrazine is a colorless solid. It is classifed as an alkylpyrazine.

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loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
nimesulide (51803-78-2)  
Aulin  ·  Nexen  ·  R 805
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems.
thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
sulfasalazine (599-79-1)  
Azulfidine  ·  Pleon  ·  Sulphasalazine
Sulfasalazine (SSZ), sold under the trade name Azulfidine among others, is a medication used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is often considered as a first line treatment in rheumatoid arthritis. It is taken by mouth.
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
5-Aminosalicylic acid (89-57-6)  
Mesalamine  ·  Asacol  ·  Pentasa
Mesalazine (INN, BAN), also known as mesalamine (USAN) or 5-aminosalicylic acid (5-ASA), is an aminosalicylate anti-inflammatory drug used to treat inflammatory bowel disease, including ulcerative colitis, or inflamed anus or rectum, and to maintain remission in Crohn's disease. It is sold in an oral form to maintain remission in Crohn's disease, and as a rectal suppository and an enema for the lower bowel conditions. It is generic and sold under many brand names worldwide, and there are many formulations.
Lysine acetylsalicylate (62952-06-1)  
aspirin lysine  ·  Venopirin  ·  Solusprin, monosalicylate, (L-Lys)-isomer
Solusprin (62952-06-1, 37933-78-1)  
lysine acetylsalicylate  ·  aspirin lysine  ·  Venopirin
celecoxib (169590-42-5)  
Celebrex  ·  SC58635  ·  SC-58635
Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people two years or older. Side effects include a 37% increase in incidence of major vascular events, which include nonfatal myocardial infarction, nonfatal stroke, or death from a blood vessel-related cause.
Diacerein (13739-02-1)  
Niverpharm brand of diacetylrhein  ·  diacerhein  ·  Zondar
Diacerein (INN), also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). It works by inhibiting interleukin-1 beta. An updated 2014 Cochrane review found diacerein had a small beneficial effect on pain.
oxaprozin (21256-18-8)  
Daypro  ·  Rhoxal-oxaprozin  ·  Apo-Oxaprozin
Oxaprozin, also known as Oxaprozinum, (sold under the names: Daypro, Dayrun, Duraprox) is a nonsteroidal anti-inflammatory drug (NSAID), used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically, it is a propionic acid derivative. It is available in 600 mg tablets.
azathioprine (446-86-6)  
Imuran  ·  Azothioprine  ·  Azathioprine Sodium
Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication. It is used in rheumatoid arthritis, Crohn's disease, ulcerative colitis, and in kidney transplants to prevent rejection. It is taken by mouth or injected into a vein.
acemetacin (53164-05-9)  
Acemetacin Stada  ·  acemetacin monohydrate  ·  ct-Arzneimittel brand of acemetacin
Acemetacin is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. It is manufactured by Merck KGaA under the tradename Emflex, and is available in the UK and other countries as a prescription-only drug.
Andrographolide (5508-58-7)  
isoandrographolide  ·  17-hydro-9-dehydro-andrographolide
Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance. Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke.
NITAZOXANIDE (55981-09-4)  
NTZ  ·  Daxon  ·  Alinia
Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is indicated for the treatment of infection by Cryptosporidium parvum and Giardia lamblia in immunocompetent individuals and has been repurposed for the treatment of influenza. Nitazoxanide has also been shown to have in vitro antiparasitic activity and clinical treatment efficacy for infections caused by other protozoa and helminths; emerging evidence suggests that it possesses efficacy in treating a number of viral infections as well.
1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)  
brobenzoxaldine, broxyquinoline drug combination  ·  Intestopan  ·  Enteroquin
nabumetone (42924-53-8)  
Relafen  ·  Relif  ·  Nabucox
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran.
rofecoxib (162011-90-7)  
Rofecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that has now been withdrawn over safety concerns. It was marketed by Merck & Co. to treat osteoarthritis, acute pain conditions, and dysmenorrhea.
BENZYDAMINE (642-72-8)  
Tantum  ·  Benzydamine Hydrochloride  ·  Chefaro Brand of Benzydamine Hydrochloride
Benzydamine (also known as Tantum Verde and branded in some countries as Difflam and Septabene), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions of the mouth and throat.
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