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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, CYP17A1 inhibitors, Anti-diabetic drugs, Hormonal agents, Sex hormones, Antineoplastic drugs

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Antiandrogens (1)
Antiglucocorticoids (1)
Antineoplastic and immunomodulating drugs (1)
Aromatase inhibitors (1)
Drugs acting on the gastrointestinal system and metabolism (1)
Hormonal antineoplastic drugs (1)
PPAR agonists (1)
Pharmaceuticals (1)
Systemic hormonal preparations (1)
Thiazolidinediones (1)

troglitazone (97322-87-7)  
Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for patients with diabetes mellitus type 2. It was developed by Daiichi Sankyo (Japan).

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1,3,5-tris(3-isocyanato-4-methylphenyl)-1,3,5-triazinane-2,4,6-trione (26603-40-7, 8060-82-0)  
brobenzoxaldine, broxyquinoline drug combination  ·  Intestopan  ·  Enteroquin
thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
metformin (1115-70-4, 657-24-9)  
Glucophage  ·  Metformin Hydrochloride  ·  Metformin HCl
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.
leflunomide (75706-12-6)  
Arava  ·  HWA 486  ·  Aventis Pharma Brand of Leflunomide
Leflunomide (original brand name Arava) is an immunosuppressive disease-modifying antirheumatic drug (DMARD), used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. It is a pyrimidine synthesis inhibitor that works by inhibiting dihydroorotate dehydrogenase.
Metformin hydrochloride (15537-72-1, 1115-70-4)  
Metformin  ·  Glucophage  ·  Metformin HCl
Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.
Imatinib (152459-95-5)  
Imatinib, sold under the brand names Gleevec among others, is a medication used to treat cancer. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that is Philadelphia chromosome-positive (Ph+) and certain types of gastrointestinal stromal tumors (GIST), systemic mastocytosis, and myelodysplastic syndrome. It is taken by mouth.
formestane (566-48-3)  
Formestane, sold under the brand name Lentaron among others, is a steroidal, selective aromatase inhibitor which is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced.
loperamide (53179-11-6)  
Imodium  ·  Loperamide Hydrochloride  ·  Loperamide Monohydrochloride
Loperamide, sold under the brand name Imodium among others, is a medication used to decrease the frequency of diarrhea. It is often used for this purpose in gastroenteritis, inflammatory bowel disease, and short bowel syndrome. It is not recommended for those with blood in the stool.
azathioprine (446-86-6)  
Imuran  ·  Azothioprine  ·  Azathioprine Sodium
Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication. It is used in rheumatoid arthritis, Crohn's disease, ulcerative colitis, and in kidney transplants to prevent rejection. It is taken by mouth or injected into a vein.
bicalutamide (90357-06-5)  
Casodex  ·  4'-cyano-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methyl-3'-(trifluoromethyl)propionanilide  ·  ICI 176334
Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat advanced prostate cancer. Bicalutamide may also be used to treat excessive hair growth in women, as a component of feminizing hormone therapy for transgender women, to treat early puberty in boys, and to prevent overly long-lasting erections in men.
ethisterone (434-03-7)  
Pregneninolone  ·  Anhydrohydroxyprogesterone  ·  17 alpha Ethynyltestosterone
Ethisterone (brand names Proluton C, Pranone among others), also known as ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a progestin with androgenic activity which was derived from testosterone and was introduced for medical use in 1939. It was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (synthetic progestogen) to be introduced. Although ethisterone has largely been superseded by newer drugs and is now little used, it reportedly continues to be available in some countries.
2,4-THIAZOLIDINEDIONE (2295-31-0)  
thiazolidinedione  ·  T-174  ·  2,4-thiazolidinedione potassium
The thiazolidinediones , abbreviated as TZD, also known as glitazones after the prototypical drug ciglitazone, are a class of heterocyclic compounds consisting of a five-membered C3NS ring. The term usually refers to a family of drugs used in the treatment of diabetes mellitus type 2 that were introduced in the late 1990s.
Melatonin (8041-44-9, 73-31-4)  
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
121-30-2 (121-30-2)  
2-ACBDS  ·  2-amino-4-chloro-m-benzenedisulfonamide  ·  4-amino-6-chloro-1,3-benzenedisulfonamide
camptothecin (7689-03-4)  
Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E.
colchicine (64-86-8)  
Colchicine, (+-)-Isomer  ·  Colchicine, (R)-Isomer
Colchicine is a medication most commonly used to treat gout. It is a toxic natural product and secondary metabolite, originally extracted from plants of the genus Colchicum (autumn crocus, Colchicum autumnale, also known as "meadow saffron"). Adverse effects are primarily gastrointestinal upset at high doses.
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