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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Hormonal contraception, Progestogens

Categories

Cyclic compounds (1)
Estrogens (1)
Five-membered rings (1)
Hormonal agents (1)
Sex hormones (1)
Six-membered rings (1)
Spiro compounds (1)
Systemic hormonal preparations (1)
Tetrahydrofurans (1)
Tetrahydropyrans (1)

DIOSGENIN (512-04-9)  
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro. The sugar-free (aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products.

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Levonorgestrel (797-63-7, 6533-00-2)  
Plan B  ·  Norplant  ·  Mirena
Norgestrel, sold under the brand name Ovral among others, is a progestin that is used in combination with an estrogen in hormonal contraceptives. It has also been used as an emergency contraceptive in the Yuzpe regimen.
ethinyl estradiol (57-63-6)  
Estinyl  ·  Ethinyloestradiol  ·  Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
Drospirenone (67392-87-4)  
ZK30595  ·  6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton  ·  ZK 30595
Drospirenone is a progestin used in birth control pills and in menopausal hormone therapy for the treatment of menopausal symptoms. In addition to its progestogenic activity, it also has antiandrogenic and antimineralocorticoid activity. It is sold as a combined birth control pill under the brand names Yasmin (US, EU, Latin America), Jasmine (France), Yarina (Russia) in a dosage containing drospirenone 3 mg/ethinylestradiol 30 µg.
Dienogest (65928-58-7)  
Dienogest, sold under the brand names Dinagest, Natazia, Qlaira, Valette, and Visanne among others, is a progestin which is available both in combination with estrogen for use in hormonal contraception and menopausal hormone therapy and by itself for the treatment of endometriosis. It has some antiandrogenic activity in addition to its progestogenic effects and as a result may improve symptoms of androgen-dependent conditions like acne.
norethindrone (68-22-4)  
Norethisterone  ·  Micronor  ·  Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
Norethisterone enanthate (3836-23-5)  
norethindrone enanthate  ·  norethisterone oenanthate  ·  19-norethindrone enanthate
Norethisterone enanthate (NETE), also known as norethindrone enanthate, is a form of progestogen-only injectable birth control. It may be used following childbirth, miscarriage, or abortion. The failure rate per year in preventing pregnancy is 2 per 100 women.
dydrogesterone (152-62-5)  
Duphaston  ·  Isopregnenone  ·  6 Dehydro 9 beta 10 alpha progesterone
Dydrogesterone, sold under the brand name Duphaston among others, is a progestin medication which is used for a variety of indications, including threatened or recurrent miscarriage during pregnancy, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, premenstrual syndrome, and as a component of menopausal hormone therapy. It is taken by mouth. Dydrogesterone is safe and well-tolerated.
ethisterone (434-03-7)  
Pregneninolone  ·  Anhydrohydroxyprogesterone  ·  17 alpha Ethynyltestosterone
Ethisterone (brand names Proluton C, Pranone among others), also known as ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a progestin with androgenic activity which was derived from testosterone and was introduced for medical use in 1939. It was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (synthetic progestogen) to be introduced. Although ethisterone has largely been superseded by newer drugs and is now little used, it reportedly continues to be available in some countries.
danazol (17230-88-5)  
Danocrine  ·  Azol  ·  Danol
Danazol, sold under the brand names Danatrol, Danocrine, Danol, and Danoval among many others, is a synthetic steroid that is used primarily in the treatment of endometriosis. It was approved by the U.S. Food and Drug Administration in 1971 as the first drug in the country to specifically treat this condition.
LYNESTRENOL (52-76-6)  
Ethinylestrenol  ·  Linestrenol  ·  Lynestrenol, (9 beta, 10 alpha,17 alpha)-Isomer
Lynestrenol is a progestin which is used in oral contraceptives in combination with an estrogen and in the treatment of gynecological disorders. It is has potent progestogenic effects on the uterine endometrium (transforming proliferative endometrium into secretory one), inhibits secretion of gonadotropins, suppresses maturation of follicles in the ovaries and ovulation, and reduces menstrual bleeding.
Medroxyprogesterone acetate (71-58-9)  
Provera  ·  DepoProvera  ·  Depo Provera
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. It is used as birth control and as part of menopausal hormone therapy. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer.
ETONOGESTREL (54048-10-1)  
Implanon  ·  Nourypharma brand of 3-keto-desogestrel  ·  nexplanon
Etonogestrel, sold under a number of brand names, is a progestin used in hormonal contraceptives, most notably the etonogestrel contraceptive implant (Nexplanon, Implanon) and the contraceptive vaginal ring (NuvaRing, Circlet). It was first introduced, as Implanon in Indonesia, in 1998, and was subsequently marketed in the United Kingdom shortly thereafter and in the United States in 2006. Etonogestrel is less androgenic than levonorgestrel and norethisterone, and it does not cause a decrease in sex hormone-binding globulin levels.
Norminest (37270-71-6)  
Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders. The medication available in low-dose and high-dose formulations and is used alone or in combination with an estrogen. It is taken by mouth.
methyltestosterone (262423-02-9, 58-18-4)  
Android  ·  Oreton  ·  Metandren
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women. It is taken by mouth. Side effects of methyltestosterone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.
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