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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Hydroxamic acids

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Genito-urinary system drug (2)
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acetohydroxamic acid (546-88-3)  
Lithostat  ·  Mission brand of acetohydroxamic acid  ·  Robert brand of acetohydroxamic acid
Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme.
Salicylhydroxamic acid (89-73-6)  
SHAM  ·  salicylhydroxamate
Salicylhydroxamic acid (SHA or SHAM) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme. It is also a trypanocidal agent.

Related Results:
actinonin (13434-13-4)  
Actinonin is a naturally occurring antibacterial agent that has demonstrated anti-tumor activity.
7797-81-1 (7797-81-1)  
N-(OH)NaPhI  ·  1,8 N-hydroxynaphthalimide  ·  N-hydroxynaphthalimide
Vorinostat (149647-78-9)  
Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities. Vorinostat is marketed under the name Zolinza ( zoh-LIN-zə) by Merck for the treatment of cutaneous manifestations in patients with cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after two systemic therapies.
N-Hydroxybenzenesulfonamide (599-71-3)  
benzenesulfohydroxamic acid  ·  Piloty's acid
Entinostat (209783-80-2)  
MS 275  ·  MS-27-275  ·  N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide
Entinostat, also known as SNDX-275 and MS-275, is a benzamide histone deacetylase inhibitor undergoing clinical trials for treatment of various cancers. Entinostat inhibits class I HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM, respectively. Syndax pharmaceuticals currently holds the rights to Entinostat and recently received $26.6 million in funds to advance treatments of resistant cancers using epigenetic tools.
BENZANILIDE (93-98-1)  
Benzanilide or N-phenylbenzamide is a simple amide. Commercially available, it may be prepared by reacting benzoic acid and aniline directly.
Salicylhydroxamic acid (89-73-6)  
SHAM  ·  salicylhydroxamate
Salicylhydroxamic acid (SHA or SHAM) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme. It is also a trypanocidal agent.
acetohydroxamic acid (546-88-3)  
Lithostat  ·  Mission brand of acetohydroxamic acid  ·  Robert brand of acetohydroxamic acid
Acetohydroxamic acid (also known as AHA or Lithostat) is a drug that is a potent and irreversible inhibitor of bacterial and plant urease usually used for urinary tract infections. The molecule is similar to urea but is not hydrolyzable by the urease enzyme.
3-Benzoylpropionic acid (2051-95-8)  
benzoylpropionic acid  ·  beta-benzoylpropionic acid
4-Sulfamoylbenzoic acid (138-41-0)  
sulfamoylbenzoic acid  ·  carzenide  ·  carzenide dipotassium salt
3-nitrophenylboronic acid (13331-27-6)  
3-nitrobenzeneboronic acid  ·  m-nitrobenzeneboronic acid  ·  meta-nitrobenzeneboronic acid
Pyrazine-2-carboxylic acid (98-97-5)  
pyrazinoic acid  ·  pyrazinoate
Pyrazinoic acid is a pyrazinamide metabolite.
3-quinolineboronic acid (191162-39-7)  
quinolin-3-ylboronic acid  ·  191162-39-7
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Drugs acting on the genito-urinary system
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