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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Progestogens

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norethindrone (68-22-4)  
Norethisterone  ·  Micronor  ·  Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
progesterone (57-83-0)  
Pregnenedione  ·  Progesterone, (13 alpha,17 alpha)-(+-)-Isomer  ·  Progesterone, (9 beta,10 alpha)-Isomer
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone has a variety of important functions in the body.
kaempferol (520-18-3)  
kempferol  ·  3,4',5,7-tetrahydroxyflavone
Kaempferol is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods. Kaempferol is a yellow crystalline solid with a melting point of 276–278 °C (529–532 °F). It is slightly soluble in water and highly soluble in hot ethanol, ethers, and DMSO.
hydroxyprogesterone (604-09-1, 68-96-2)  
17 Hydroxyprogesterone  ·  17 alpha Hydroxyprogesterone  ·  17 alpha-Hydroxyprogesterone
Hydroxyprogesterone (OHP) may refer to: 3α-Hydroxyprogesterone (3α-dihydroprogesterone) 3β-Hydroxyprogesterone (3β-dihydroprogesterone) 11α-Hydroxyprogesterone 11β-Hydroxyprogesterone (21-deoxycorticosterone) 16α-Hydroxyprogesterone 17α-Hydroxyprogesterone 20α-Hydroxyprogesterone 21-Hydroxyprogesterone (11-deoxycorticosterone)
Medroxyprogesterone acetate (71-58-9)  
Provera  ·  DepoProvera  ·  Depo Provera
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. It is used as birth control and as part of menopausal hormone therapy. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer.
ETHYNODIOL DIACETATE (297-76-7)  
Continuin  ·  Femulen  ·  (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate
Etynodiol diacetate, or ethynodiol diacetate, is a progestin of the 19-nortestosterone group which is used in oral contraceptives. It is the 3β,17β-diacetate ester of etynodiol, and acts as a rapidly converted prodrug of norethisterone, with etynodiol occurring as an intermediate. Etynodiol diacetate has weak androgenic activity, and, unlike most progestins but similarly to norethisterone and noretynodrel, also has some estrogenic activity.
desoxycorticosterone (64-85-7)  
Deoxycorticosterone  ·  Cortexone  ·  11 Decorticosterone
11-Deoxycorticosterone (DOC), or simply deoxycorticosterone, also known as 21-hydroxyprogesterone, as well as desoxycortone (INN), deoxycortone, and cortexone, is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone. It is an active (Na+-retaining) mineralocorticoid. As its names indicate, 11-deoxycorticosterone can be understood as the 21-hydroxy-variant of progesterone or as the 11-deoxy-variant of corticosterone.
SYRINGIC ACID (530-57-4)  
syringic acid Cu (+2) salt (1:1)
Syringic acid is a naturally occurring O-methylated trihydroxybenzoic acid, a type of chemical compound.
20.alpha.-Progerol (145-15-3)  
20α-Dihydroprogesterone (20α-DHP), also known as 20α-hydroxyprogesterone (20α-OHP), is a naturally occurring, endogenous progestogen. It is a metabolite of progesterone, converted by the 20α-hydroxysteroid dehydrogenases AKR1C1 and AKR1C3, and although still active as a progestogen, is much less potent in comparison. It has been found to act as an aromatase inhibitor and to inhibit the production of estrogen in breast tissue in vitro.
19-Norprogesterone (472-54-8)  
19-Norprogesterone, also known as 19-norpregn-4-ene-3,20-dione, is a steroidal progestin and close analogue of the sex hormone progesterone, lacking only the C19 methyl group of that molecule. It was first synthesized in 1944 in the form of a mixture that also included unnatural stereoisomers (probably C14 (β) and C17 (α)) of progesterone, and this mixture was found to be at least equivalent to progesterone in terms of progestogenic activity. Subsequent investigations revealed that 17-isoprogesterone and 14-iso-17-isoprogesterone are devoid of progestogenic activity.
DIOSGENIN (512-04-9)  
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro. The sugar-free (aglycone) product of such hydrolysis, diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products.
Flugestone (337-03-1)  
17 beta-Acetoxy-9-fluoro-11 beta-hydroxyprogesterone  ·  Flugestone Acetate  ·  Fluorogestone Acetate
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Drugs acting on the genito-urinary system
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