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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Synthetic estrogens

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Hormonal agents (10)
Systemic hormonal preparations (10)
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Estrogens (5)
Genito-urinary system drug (5)
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Selective estrogen receptor modulators (1)
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ethinyl estradiol (57-63-6)  
Estinyl  ·  Ethinyloestradiol  ·  Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
norethindrone (68-22-4)  
Norethisterone  ·  Micronor  ·  Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)  
Stilbestrol  ·  Distilbène  ·  Stilbene Estrogen
dienestrol (35495-11-5, 84-17-3, 13029-44-2)  
Dienoestrol  ·  Ortho Dienestrol  ·  Dienestrol, (Z,E)-Isomer
Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.
ETHYNODIOL DIACETATE (297-76-7)  
Continuin  ·  Femulen  ·  (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate
Etynodiol diacetate, or ethynodiol diacetate, is a progestin of the 19-nortestosterone group which is used in oral contraceptives. It is the 3β,17β-diacetate ester of etynodiol, and acts as a rapidly converted prodrug of norethisterone, with etynodiol occurring as an intermediate. Etynodiol diacetate has weak androgenic activity, and, unlike most progestins but similarly to norethisterone and noretynodrel, also has some estrogenic activity.
meso-Hexestrol (84-16-2)  
Hexestrol  ·  Hexestrol, (R-(R*,R*))-Isomer  ·  Hexestrol, (R*,S*)-Isomer
3,4-Dihydro-2H-phenanthren-1-one (573-22-8)  
1-Keto-1,2,3,4-tetrahydrophenanthrene (THP-1), or 1,2,3,4-tetrahydrophenanthren-1-one, is a synthetic steroid-like compound which was reported to be the first synthetic estrogen, or the first synthetic compound identified with estrogenic activity. It was first synthesized in 1933 by Cook et al. and was tested due to its similarity to the presumed chemical structure of estrone.
HEXESTROL DIPROPIONATE (4825-53-0)  
Hexestrol dipropionate (brand name Hexanoestrol, Retalon Oleosum), or hexestrol dipropanoate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol. It is an ester of hexestrol, and has been known since at least 1931. The drug has been used in the past to inhibit lactation in women.

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methyltestosterone (262423-02-9, 58-18-4)  
Android  ·  Oreton  ·  Metandren
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women. It is taken by mouth. Side effects of methyltestosterone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.
ethisterone (434-03-7)  
Pregneninolone  ·  Anhydrohydroxyprogesterone  ·  17 alpha Ethynyltestosterone
Ethisterone (brand names Proluton C, Pranone among others), also known as ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a progestin with androgenic activity which was derived from testosterone and was introduced for medical use in 1939. It was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (synthetic progestogen) to be introduced. Although ethisterone has largely been superseded by newer drugs and is now little used, it reportedly continues to be available in some countries.
Melatonin (8041-44-9, 73-31-4)  
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness. Melatonin is also produced in plants where it functions as a first line of defense against oxidative stress. In animals, melatonin is involved in the entrainment (synchronization) of the circadian rhythms including sleep-wake timing, blood pressure regulation, seasonal reproduction, and many others.
estrone (19973-76-3, 53-16-7)  
Folliculin  ·  Kestrone  ·  Wehgen
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue.
estradiol (50-28-2, 73459-61-7)  
Oestradiol  ·  Estrace  ·  Vivelle
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a feminine pattern of fat distribution in women and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus, and vagina during puberty, adulthood, and pregnancy.
ethinyl estradiol (57-63-6)  
Estinyl  ·  Ethinyloestradiol  ·  Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
progesterone (57-83-0)  
Pregnenedione  ·  Progesterone, (13 alpha,17 alpha)-(+-)-Isomer  ·  Progesterone, (9 beta,10 alpha)-Isomer
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone has a variety of important functions in the body.
estriol (50-27-1)  
Epiestriol  ·  (16alpha,17beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol  ·  16beta-Hydroxy-Estradiol
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable.
testosterone (58-22-0)  
Testim  ·  Testoderm  ·  AndroGel
Testosterone is the primary male sex hormone and an anabolic steroid. In male humans, testosterone plays a key role in the development of male reproductive tissues such as testes and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. In addition, testosterone is involved in health and well-being, and the prevention of osteoporosis.
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