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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Synthetic estrogens, Genito-urinary system drug

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Hormonal agents (5)
Systemic hormonal preparations (5)
Estrogens (3)
Sex hormones (3)
Estrogen esters (2)
Ketones (1)
Pharmaceuticals (1)

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Toronto Research Chemicals (1)
TCI Chemicals (1)

estriol (50-27-1)  
Epiestriol  ·  (16alpha,17beta)-Estra-1,3,5(10)-Triene-3,16,17-Triol  ·  16beta-Hydroxy-Estradiol
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable.
EXEMESTANE (107868-30-4)  
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow.
ethinyl estradiol (57-63-6)  
Estinyl  ·  Ethinyloestradiol  ·  Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
estrone (19973-76-3, 53-16-7)  
Folliculin  ·  Kestrone  ·  Wehgen
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue.
Iminostilbene (256-96-2)  
iminostilbene, 10-(13)C-labeled
Dibenzazepine (iminostilbene) is a chemical compound with two benzene rings fused to an azepine group.
norethindrone (68-22-4)  
Norethisterone  ·  Micronor  ·  Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
Nonoxynol-9 (42173-90-0, 26571-11-9, 14409-72-4)  
Nonoxynol-9, sometimes abbreviated as N-9, is an organic compound that is used as a surfactant. It is a member of the nonoxynol family of nonionic surfactants. N-9 and related compounds are ingredients in various cleaning and cosmetic products.
Dienogest (65928-58-7)  
Dienogest, sold under the brand names Dinagest, Natazia, Qlaira, Valette, and Visanne among others, is a progestin which is available both in combination with estrogen for use in hormonal contraception and menopausal hormone therapy and by itself for the treatment of endometriosis. It has some antiandrogenic activity in addition to its progestogenic effects and as a result may improve symptoms of androgen-dependent conditions like acne.
Medroxyprogesterone acetate (71-58-9)  
Provera  ·  DepoProvera  ·  Depo Provera
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. It is used as birth control and as part of menopausal hormone therapy. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer.
2-Methylbenzenesulfonamide (8013-74-9, 1333-07-9, 88-19-7)  
OTS  ·  ortho-toluenesulphonamide  ·  o-toluenesulfonamide
mitotane (53-19-0)  
Lysodren  ·  Khloditan  ·  o,p-DDD
Mitotane, sold under the brand name Lysodren, is a steroidogenesis inhibitor and cytostatic antineoplastic medication which is used in the treatment of adrenocortical carcinoma and Cushing's syndrome. It is a derivative of p,p'-DDT and an isomer of p,p'-DDD, and is also known as 1,1-(dichlorodiphenyl)-2,2-dichloroethane (o,p'-DDD).
N-Acetyl-L-tyrosine (537-55-3)  
N-acetyltyrosine  ·  N-acetyltyrosine, (D)-isomer  ·  acetyl-L-tyrosine
clioquinol (130-26-7)  
Vioform  ·  Iodochlorhydroxyquin  ·  EnteroVioform
Clioquinol (iodochlorhydroxyquin) is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication.
hydrocortisone acetate (50-03-3)  
Cortifoam  ·  Epifoam  ·  Colifoam
Hydrocortisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
metronidazole (99616-64-5, 443-48-1)  
Metric  ·  Flagyl  ·  MetroGel
Metronidazole (MNZ), marketed under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.
MEGESTROL ACETATE (51154-23-5, 595-33-5)  
Borea  ·  Megace  ·  LinMegestrol
Megestrol acetate (abbreviated as MGA), sold under the brand name Megace, is a progestin with antiandrogen activity that is mainly used as an appetite stimulant and less commonly in the treatment of breast and endometrial cancers. It is the C17α acetate ester of megestrol, which, in contrast to MGA, was never marketed for medical use. The term megestrol is often inappropriately used as a synonym for MGA, and when it is used, it almost always refers to MGA rather actually than megestrol.
121-30-2 (121-30-2)  
2-ACBDS  ·  2-amino-4-chloro-m-benzenedisulfonamide  ·  4-amino-6-chloro-1,3-benzenedisulfonamide
formestane (566-48-3)  
Formestane, sold under the brand name Lentaron among others, is a steroidal, selective aromatase inhibitor which is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced.
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