www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Synthetic estrogens, Selective estrogen receptor modulators, Sex hormones, Triphenylethylenes, Systemic hormonal preparations, Estrogens
Hormonal agents (1)
AK Scientific (1)
TCI Chemicals (1)
Pregneninolone · Anhydrohydroxyprogesterone · 17 alpha Ethynyltestosterone
Ethisterone (brand names Proluton C, Pranone among others), also known as ethinyltestosterone, pregneninolone, or anhydrohydroxyprogesterone, is a progestin with androgenic activity which was derived from testosterone and was introduced for medical use in 1939. It was the second progestogen to be marketed (intramuscular progesterone was introduced as Proluton in 1934) and was both the first orally active progestogen and the first progestin (synthetic progestogen) to be introduced. Although ethisterone has largely been superseded by newer drugs and is now little used, it reportedly continues to be available in some countries.
Pregnenedione · Progesterone, (13 alpha,17 alpha)-(+-)-Isomer · Progesterone, (9 beta,10 alpha)-Isomer
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone has a variety of important functions in the body.
Dirigestran (33515-09-2, 6918-09-8, 9002-67-9, 9034-40-6)
GnRH · LHRH · Gonadotropin Releasing Hormone
Gonadorelin, also known as gonadotropin-releasing hormone (GnRH) and sold under the brand names Factrel, HRF, Kryptocur, Lutrelef, Lutrepulse, and Relefact among others, is a GnRH agonist which is used in fertility medicine and to treat amenorrhea and hypogonadism. It is also used in veterinary medicine. The drug is a pharmaceutical form of endogenous GnRH and is identical to it in chemical structure.
estradiol (50-28-2, 73459-61-7)
Oestradiol · Estrace · Vivelle
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a feminine pattern of fat distribution in women and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus, and vagina during puberty, adulthood, and pregnancy.
methyltestosterone (262423-02-9, 58-18-4)
Android · Oreton · Metandren
Methyltestosterone, sold under the brand names Android, Metandren, and Testred among others, is an androgen and anabolic steroid (AAS) medication which is used in the treatment of low testosterone levels in men, delayed puberty in boys, at low doses as a component of menopausal hormone therapy for menopausal symptoms like hot flashes, osteoporosis, and low sexual desire in women, and to treat breast cancer in women. It is taken by mouth. Side effects of methyltestosterone include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.
ethinyl estradiol (57-63-6)
Estinyl · Ethinyloestradiol · Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
Estradiol mustard (22966-79-6)
Estradiol mustard (developmental code name NSC-112259), also known as chlorphenacyl estradiol diester, as well as estradiol 3,17β-bis(4-(bis(2-chloroethyl)amino)phenyl)acetate, is a synthetic, steroidal estrogen and alkylating antineoplastic agent and a chlorphenacyl nitrogen mustard-coupled estrogen ester that was never marketed. It is selectively distributed into estrogen receptor (ER)-positive tissues such as ER-expressing tumors like those seen in breast and prostate cancers. For this reason, estradiol mustard and other cytostatic-linked estrogens like estramustine phosphate have reduced toxicity relative to non-linked nitrogen mustard alkylating antineoplastic agents.
ESTRADIOL UNDECYLATE (3571-53-7)
Estradiol undecylate, or estradiol undecanoate, sold under the brand name Progynon Depot 100 among others, is a medication which has been used in the treatment of prostate cancer in men. It has also been used as a part of hormone therapy for transgender women. Although estradiol undecylate has been used in the past, it has mostly or fully been discontinued and hence is now mostly or fully no longer available.
estradiol benzoate (50-50-0)
Eston-B · 17beta-estradiol-3-benzoate · estradiol 3-benzoate
Estradiol benzoate, sold under the brand name Progynon-B among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in veterinary medicine. It is given by injection into muscle. Side effects of estradiol benzoate include breast tenderness, breast enlargement, nausea, headache, and fluid retention.
estradiol cypionate (313-06-4)
Depo-estradiol · estradiol 17 beta-cyclopentylpropionate · estradiol 17 beta-cypionate
Estradiol cypionate, sold under the brand name Depo-Estradiol among others, is a medication which is used in hormone therapy such as for menopausal symptoms and in hormonal birth control. It is given by injection into muscle. Side effects of estradiol cypionate include breast tenderness, breast enlargement, nausea, headache, and fluid retention.
testosterone enanthate (315-37-7)
Delatestryl · Andropository · Durathate
Testosterone enanthate, sold under the brand name Delatestryl among others, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men. It is also used in hormone therapy for transgender men. It is given by injection into muscle usually once every two to four weeks.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)
Stilbestrol · Distilbène · Stilbene Estrogen
estrone (19973-76-3, 53-16-7)
Folliculin · Kestrone · Wehgen
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue.
Testim · Testoderm · AndroGel
Testosterone is the primary male sex hormone and an anabolic steroid. In male humans, testosterone plays a key role in the development of male reproductive tissues such as testes and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair. In addition, testosterone is involved in health and well-being, and the prevention of osteoporosis.
Eulexin · Euflex · SCH 13521
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. It is also used in the treatment of androgen-dependent conditions like acne, excessive hair growth, and high androgen levels in women. It is taken by mouth, usually three times per day.
Formestane, sold under the brand name Lentaron among others, is a steroidal, selective aromatase inhibitor which is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced.
Dienogest, sold under the brand names Dinagest, Natazia, Qlaira, Valette, and Visanne among others, is a progestin which is available both in combination with estrogen for use in hormonal contraception and menopausal hormone therapy and by itself for the treatment of endometriosis. It has some antiandrogenic activity in addition to its progestogenic effects and as a result may improve symptoms of androgen-dependent conditions like acne.
DHEA · Dehydroisoandrosterone · Androstenolone
Prasterone, also known as dehydroepiandrosterone (DHEA), is a naturally occurring steroid which is used as a supplement and medication. It is an androstane derivative and a precursor of steroid hormones like testosterone and estradiol. Prasterone has weak androgenic activity, weak estrogenic activity, and neurosteroid activity, and acts as a prohormone of androgens and estrogens depending on its dosage and route of administration.