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www.sigmaaldrich.com, Drugs acting on the genito-urinary system, Systemic hormonal preparations

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Hormonal agents (45)
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Resveratrol (501-36-0)  
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries. Although it is used as a dietary supplement, there is no good evidence that consuming resveratrol affects life expectancy or human health.
ethinyl estradiol (57-63-6)  
Estinyl  ·  Ethinyloestradiol  ·  Ethynyl Estradiol
Ethinylestriol (EE3), or 17α-ethynylestriol, also known as 17α-ethynylestra-1,3,5(10)-triene-3,16α,17β-triol, is a synthetic, steroidal estrogen that was never marketed. Nilestriol, the 3-cyclopentyl ether of ethinylestriol, is a prodrug of ethinylestriol, and is a more potent estrogen in comparison, but, similarly to ethinylestriol, was never marketed. Ethinylestriol has been found to reduce the risk of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary cancer when given as a prophylactic in animal models, while other estrogens like ethinylestradiol and diethylstilbestrol were ineffective.
thalidomide (50-35-1)  
Thalomid  ·  Celgene Brand of Thalidomide  ·  Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
p,p'-DDE (68679-99-2, 72-55-9)  
DDE  ·  DDX  ·  DDMU
Dichlorodiphenyldichloroethylene (DDE) is a chemical compound formed by the loss of hydrogen chloride (dehydrohalogenation) from DDT, of which it is one of the more common breakdown products. Due to DDT’s massive prevalence in society and agriculture during the mid 20th century, DDT and DDE are still widely seen in animal tissue samples. DDE is particularly dangerous because it is fat-soluble like other organochlorines, thus it is rarely excreted from the body and concentrations tend to increase throughout life.
Carbamazepine (298-46-4)  
Tegretol  ·  Neurotol  ·  Epitol
Carbamazepine (CBZ), sold under the tradename Tegretol among others, is a medication used primarily in the treatment of epilepsy and neuropathic pain. It is not effective for absence seizures or myoclonic seizures. It is used in schizophrenia along with other medications and as a second line agent in bipolar disorder.
phenothrin (26002-80-2)  
Sumithrin  ·  d-phenothrin  ·  (3-phenoxyphenyl)methyl cis,trans-(+)-2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate
Phenothrin, also called sumithrin and d-phenothrin, is a synthetic pyrethroid that kills adult fleas and ticks. It has also been used to kill head lice in humans. d-Phenothrin is used as a component of aerosol insecticides for domestic use.
norethindrone (68-22-4)  
Norethisterone  ·  Micronor  ·  Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
estradiol (50-28-2, 73459-61-7)  
Oestradiol  ·  Estrace  ·  Vivelle
Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips, and a feminine pattern of fat distribution in women and is important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus, and vagina during puberty, adulthood, and pregnancy.
VINCLOZOLIN (50471-44-8)  
Ronilan  ·  3-(3,5-dichlorophenyl)-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione
Vinclozolin (trade names Ronilan, Curalan, Vorlan, Touche) is a common dicarboximide fungicide used to control diseases, such as blights, rots and molds in vineyards, and on fruits and vegetables such as raspberries, lettuce, kiwi, snap beans, and onions. It is also used on turf on golf courses. Two common fungi that vinclozolin is used to protect crops against are Botrytis cinerea and Sclerotinia sclerotiorum.
progesterone (57-83-0)  
Pregnenedione  ·  Progesterone, (13 alpha,17 alpha)-(+-)-Isomer  ·  Progesterone, (9 beta,10 alpha)-Isomer
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species. It belongs to a group of steroid hormones called the progestogens, and is the major progestogen in the body. Progesterone has a variety of important functions in the body.
METHIOCARB (2032-65-7)  
Methiocarb is a carbamate pesticide which is used as a bird repellent, insecticide, acaricide and molluscicide since the 1960s. Carbamates are widely used in agriculture as insecticides and herbicides. They are preferred instead of organochlorines because organochlorines are long lasting persistent in crops.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)  
Stilbestrol  ·  Distilbène  ·  Stilbene Estrogen
Pioglitazone (111025-46-8)  
Actos  ·  pioglitazone hydrochloride  ·  U72,107A
Pioglitazone (brand name Actos) is a prescription drug of the thiazolidinedione (TZD) class with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes. While pioglitazone does decrease blood sugar levels, studies on the main cardiovascular outcomes have not yielded statistically significant results. Its cardiovascular safety profile compares favorably with that of rosiglitazone, which was withdrawn from some markets after concerns about an increased risk of cardiac events.
OXYTOCIN (50-56-6)  
Pitocin  ·  Syntocinon  ·  Ocytocin
Oxytocin (Oxt; , ) is a peptide hormone and neuropeptide. Oxytocin is normally produced by the paraventricular nucleus of the hypothalamus and released by the posterior pituitary. It plays a role in social bonding, sexual reproduction in both sexes, and during and after childbirth.
rosiglitazone (122320-73-4)  
Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride.
BISPHENOL A DIGLYCIDYL ETHER (1675-54-3, 500008-19-5)  
DGEBA  ·  DGEBPA  ·  2,2-bis(p-glycidyloxyphenyl)propane
Bisphenol A diglycidyl ether (commonly abbreviated BADGE or DGEBA) is an organic compound used as constituent of epoxy resins. The compound is a colorless solid (commercial samples can appear yellow) that melts slightly above room temperature.
dienestrol (35495-11-5, 84-17-3, 13029-44-2)  
Dienoestrol  ·  Ortho Dienestrol  ·  Dienestrol, (Z,E)-Isomer
Dienestrol (INN, USAN) (brand names Ortho Dienestrol, Dienoestrol, Dienoestrol Ortho, Sexadien, Denestrolin, Dienol, Dinovex, Follormon, Oestrodiene, Synestrol, numerous others), also known as dienoestrol (BAN), is a synthetic nonsteroidal estrogen of the stilbestrol group which is or was used to treat menopausal symptoms in the United States and Europe. It was introduced in the U.S. in 1947 by Schering as Synestrol and in France in 1948 as Cycladiene.
clotrimazole (23593-75-1)  
Lotrimin  ·  Mycelex  ·  Canesten
Clotrimazole, sold under the brand name Canesten among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, pityriasis versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.
troglitazone (97322-87-7)  
Troglitazone (Rezulin, Resulin, Romozin, Noscal) is an antidiabetic and anti-inflammatory drug, and a member of the drug class of the thiazolidinediones. It was prescribed for patients with diabetes mellitus type 2. It was developed by Daiichi Sankyo (Japan).
hydroxyprogesterone (604-09-1, 68-96-2)  
17 Hydroxyprogesterone  ·  17 alpha Hydroxyprogesterone  ·  17 alpha-Hydroxyprogesterone
Hydroxyprogesterone (OHP) may refer to: 3α-Hydroxyprogesterone (3α-dihydroprogesterone) 3β-Hydroxyprogesterone (3β-dihydroprogesterone) 11α-Hydroxyprogesterone 11β-Hydroxyprogesterone (21-deoxycorticosterone) 16α-Hydroxyprogesterone 17α-Hydroxyprogesterone 20α-Hydroxyprogesterone 21-Hydroxyprogesterone (11-deoxycorticosterone)
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