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www.sigmaaldrich.com, Phenethylamines

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Drugs acting on the nervous system (59)
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epinephrine (51-43-4)  
Adrenaline  ·  Epinephrine Hydrochloride  ·  Epinephrine Bitartrate
Epinephrine, also known as adrenalin or adrenaline, is a hormone, neurotransmitter, and medication. Epinephrine is normally produced by both the adrenal glands and certain neurons. It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil dilation, and blood sugar.
levodopa (587-45-1, 59-92-7)  
Larodopa  ·  Dopar  ·  Levopa
L-DOPA (), also known as levodopa () or L-3,4-dihydroxyphenylalanine is an amino acid that is made and used as part of the normal biology of humans, some animals and plants. Some animals and humans make it via biosynthesis from the amino acid L-tyrosine. L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines.
AMPHETAMINE (60-15-1, 300-62-9)  
Amphetamine Sulfate  ·  Levoamphetamine  ·  Phenamine
Amphetamine (contracted from alpha-methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers, levoamphetamine and dextroamphetamine, in their pure amine forms.
Phenelzine (51-71-8)  
Nardil  ·  Phenelzine Sulfate  ·  2 Phenethylhydrazine
Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic. Along with tranylcypromine and isocarboxazid, phenelzine is one of the few non-selective and irreversible MAOIs still in widespread clinical use. It is typically available in 15 mg tablets and doses usually range from 30–90 mg per day, with 15 mg every day or every other day suggested as a maintenance dose following a successful course of treatment.
phentermine (122-09-8)  
Phentermine Hydrochloride  ·  Adipex P  ·  Adipex-P
Phentermine (contracted from phenyl-tertiary-butylamine), also known as α,α-dimethylphenethylamine, is a psychostimulant drug of the substituted amphetamine chemical class, with pharmacology similar to amphetamine. It is used medically as an appetite suppressant for short term use, as an adjunct to exercise and reducing calorie intake. Phentermine may produce cardiovascular, gastrointestinal, and CNS side effects; rare cases of pulmonary hypertension and cardiac valvular disease have been reported.
DL-DOPA (63-84-3)  
Dopa  ·  Dihydroxyphenylalanine  ·  3,4 Dihydroxyphenylalanine
Desvenlafaxine (93413-62-8)  
Desvenlafaxine (brand name: Pristiq, Desfax, Ellefore), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause.
METHAMPHETAMINE (51-57-0, 537-46-2)  
Desoxyn  ·  Methylamphetamine  ·  Methamphetamine Hydrochloride
Methamphetamine (contracted from N-methylamphetamine) is a strong central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. Methamphetamine properly refers to a specific chemical, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms.
chloramphenicol (56-75-7, 2787-09-9)  
Chloromycetin  ·  Ophthochlor  ·  Cloranfenicol
Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever.
(-)-Norephedrine (492-41-1, 14838-15-4, 700-65-2)  
Phenylpropanolamine  ·  Phenylpropanolamine Hydrochloride  ·  Norephedrine
Norephedrine (36393-56-3, 14838-15-4, 37577-28-9, 700-65-2)  
Phenylpropanolamine  ·  Phenylpropanolamine Hydrochloride  ·  Dexatrim
Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs.
methyldopa (555-30-6, 41372-08-1)  
Aldomet  ·  Methyldopate  ·  alpha Methyldopa
Methyldopa, sold under the brand name Aldomet among others, is a medication used for high blood pressure. It is one of the preferred treatments for high blood pressure in pregnancy. For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred.
phenylephrine (59-42-7, 1416-03-1)  
Phenylephrine Hydrochloride  ·  Neosynephrine  ·  Phenylephrine Tannate
Phenylephrine is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Phenylephrine is marketed as an alternative for the decongestant pseudoephedrine, although clinical trials show phenylephrine, taken orally at the recommended dose, to be no more effective than placebo for allergy relief. Phenylephrine can also cause a decrease in heart rate through reflex bradycardia.
Salbutamol (18559-94-9)  
Albuterol  ·  Ventolin  ·  Proventil
Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs. It is used to treat asthma including asthma attacks, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease (COPD). It may also be used to treat high blood potassium levels.
Phenethylamine (64-04-0)  
2-phenethylamine  ·  phenethylamine hydrobromide  ·  phenethylamine sulfate (2:1)
Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans. Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system. It is biosynthesized from the amino acid L-phenylalanine by enzymatic decarboxylation via the enzyme aromatic L-amino acid decarboxylase.
droxidopa (3916-18-5, 23651-95-8)  
3,4 threo DOPS  ·  3,4-threo-DOPS  ·  Droxidopa, (DL-Tyr)-Isomer
Droxidopa (INN; trade name Northera; also known as L-DOPS, L-threo-dihydroxyphenylserine, L-threo-DOPS and SM-5688) is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine (noradrenaline). Unlike norepinephrine, droxidopa is capable of crossing the protective blood–brain barrier (BBB).
tyramine (51-67-2)  
p-Tyramine  ·  4-(2-Aminoethyl)phenol  ·  4 Hydroxyphenethylamine
Tyramine (also spelled tyramin) ( TY-rə-meen), also known by several other names, is a naturally occurring trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects following ingestion.
nylidrin (447-41-6)  
Arlidin  ·  Nylidrin Hydrochloride  ·  Dilatol
Buphenine (or nylidrin) is a β2 adrenoreceptor agonist that acts as a vasodilator.
levonordefrin (829-74-3, 74812-63-8)  
Corbadrine (INN; marketed as Neo-Cobefrine), also known as levonordefrin (USAN) and α-methylnorepinephrine, is a catecholamine sympathomimetic used as a topical nasal decongestant and vasoconstrictor in dentistry in the United States, (usually in a pre-mixed solution with local anesthetics, such as mepivacaine). Corbadrine is also a metabolite of the antihypertensive drug methyldopa, and plays a role in its pharmacology and effects.
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