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www.tcichemicals.com, Drugs acting on the cardiovascular system

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Theophylline (58-55-9)  
Theon  ·  Constant T  ·  Elixophyllin
Theophylline, also known as 1,3-dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine, and is readily found in nature, and is present in tea (Camellia sinensis) and cocoa (Theobroma cacao). A small amount of theophylline is one of the products of caffeine metabolic processing in the liver.
hydrochlorothiazide (58-93-5)  
HydroDIURIL  ·  HCTZ  ·  Esidrix
Hydrochlorothiazide (HCTZ or HCT) is a diuretic medication often used to treat high blood pressure and swelling due to fluid build up. Other uses include diabetes insipidus, renal tubular acidosis, and to decrease the risk of kidney stones in those with high calcium level in the urine. For high blood pressure it is often recommended as a first line treatment.
Phenytoin (57-41-0, 630-93-3)  
Dilantin  ·  Diphenylhydantoin  ·  Phenytoin Sodium
Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication. It is useful for the prevention of tonic-clonic seizures and partial seizures, but not absence seizures. The intravenous form is used for status epilepticus that does not improve with benzodiazepines.
epinephrine (51-43-4)  
Adrenaline  ·  Epinephrine Hydrochloride  ·  Epinephrine Bitartrate
Epinephrine, also known as adrenalin or adrenaline, is a hormone, neurotransmitter, and medication. Epinephrine is normally produced by both the adrenal glands and certain neurons. It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil dilation, and blood sugar.
4-aminopyridine (504-24-5)  
VMI103  ·  Fampridine SR  ·  Fampridine-SR
4-Aminopyridine (4-AP, fampridine, dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used as a research tool in characterizing subtypes of the potassium channel.
Aripiprazole (129722-12-9)  
Aripiprazole, sold under the brand name Abilify among others, is an atypical antipsychotic. From April 2013 to March 2014, sales of Abilify amounted to almost $6.9 billion.. It is recommended by some doctors and used in the treatment of schizophrenia and bipolar disorder.
zonisamide (68291-97-4)  
Zonisamide is a medication used to treat the symptoms of epilepsy and Parkinson's disease. Chemically it is a sulfonamide. It serves as an anticonvulsant used primarily as an adjunctive therapy in adults with Parkinson's disease, partial-onset seizures; infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic and generalized tonic clonic seizure.
nicotinic acid (59-67-6)  
Niacin  ·  Nicotinate  ·  Nicolar
Niacin, also known as nicotinic acid, is an organic compound and is, depending on the definition used, one of the 20 to 80 essential human nutrients. Together with nicotinamide it makes up the group known as vitamin B3 complex. It has the formula C 6H 5NO 2 and belongs to the group of the pyridinecarboxylic acids.
Risperidone (106266-06-2)  
Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication. It is mainly used to treat schizophrenia, bipolar disorder, and irritability in people with autism. It is taken either by mouth or by injection into a muscle.
Furosemide (54-31-9, 106391-48-4)  
Lasix  ·  Frusemide  ·  Furosemide Monohydrochloride
Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It may also be used for the treatment of high blood pressure. It can be taken intravenously or by mouth.
D-Sorbitol (50-70-4)  
Sorbitol  ·  Medevac  ·  Yal
Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the aldehyde group to a hydroxyl group. Most sorbitol is made from corn syrup, but it is also found in nature, for example in apples, pears, peaches, and prunes.
nifedipine (21829-25-4)  
Procardia  ·  Adalat  ·  Procardia XL
Nifedipine, sold under the brand names Adalat among others, is a medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. It is one of the treatments of choice for Prinzmetal angina. It may be used to treat severe high blood pressure in pregnancy.
gemfibrozil (25812-30-0)  
Lopid  ·  Pilder  ·  CI719
Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid.
primidone (125-33-7)  
Mysoline  ·  Sertan  ·  AstraZeneca Brand of Primidone
Primidone (INN, BAN, USP) is an anticonvulsant of the barbiturate class. It is a structural analog of phenobarbital and related to barbiturate-derivative anticonvulsants. The active metabolites, phenobarbital, p-hydroxyphenobarbital, and phenylethylmalonamide, are also anticonvulsants.
Cilostazol (73963-72-1)  
Pletal  ·  6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone  ·  OPC 13013
Cilostazol is a quinolinone-derivative medication used in the alleviation of the symptoms of intermittent claudication in individuals with peripheral vascular disease. It is manufactured by Otsuka Pharmaceutical Co. under the trade name Pletaal.
fenofibrate (49562-28-9)  
CiL  ·  Tricor  ·  Lofibra
Fenofibrate, marketed as Tricor and under several other brand names, is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in people at risk of cardiovascular disease. Like other fibrates, it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density lipoprotein (HDL) levels and reducing triglyceride levels.
digitoxin (8006-96-0, 71-63-6, 87112-48-9)  
Digitaline Nativelle  ·  corax Brand of Digitoxin  ·  Chauvin Brand of Digitoxin
Digitoxin is a cardiac glycoside. It is a phytosteroid and is similar in structure and effects to digoxin (though the effects are longer-lasting). Unlike digoxin (which is eliminated from the body via the kidneys), it is eliminated via the liver, so could be used in patients with poor or erratic kidney function.
methyldopa (555-30-6, 41372-08-1)  
Aldomet  ·  Methyldopate  ·  alpha Methyldopa
Methyldopa, sold under the brand name Aldomet among others, is a medication used for high blood pressure. It is one of the preferred treatments for high blood pressure in pregnancy. For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred.
Eplerenone (107724-20-9)  
Eplerenone is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure. Classed as a selective aldosterone receptor antagonist (SARA), it is similar to the diuretic spironolactone, though it is much more selective for the mineralocorticoid receptor in comparison (i.e., does not possess any antiandrogen, progestogen, glucocorticoid, or estrogenic effects), and is specifically marketed for reducing cardiovascular risk in patients following myocardial infarction. Eplerenone is a potassium-sparing diuretic, meaning that it helps the body get rid of water but still keep potassium.
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