Hormonal agents (16)
Cyclic compounds (4)
Food Additives (2)
Essential oils (1)
Estrogen esters (1)
PPAR agonists (1)
Sigma Aldrich (25)
AK Scientific (14)
Oakwood Chemical (5)
Metox · DMDT · Dianisyl Trichloroethane
Methoxychlor is a synthetic organochlorine used as an insecticide.
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or, when the plant is under attack by pathogens such as bacteria or fungi. Sources of resveratrol in food include the skin of grapes, blueberries, raspberries, mulberries. Although it is used as a dietary supplement, there is no good evidence that consuming resveratrol affects life expectancy or human health.
Thalomid · Celgene Brand of Thalidomide · Sedoval
Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs. Today, thalidomide is used mainly as a treatment of certain cancers (multiple myeloma) and of a complication of leprosy. Thalidomide was first marketed in 1957 in West Germany under the trade-name Contergan.
p,p'-DDE (68679-99-2, 72-55-9)
DDE · DDX · DDMU
Dichlorodiphenyldichloroethylene (DDE) is a chemical compound formed by the loss of hydrogen chloride (dehydrohalogenation) from DDT, of which it is one of the more common breakdown products. Due to DDT’s massive prevalence in society and agriculture during the mid 20th century, DDT and DDE are still widely seen in animal tissue samples. DDE is particularly dangerous because it is fat-soluble like other organochlorines, thus it is rarely excreted from the body and concentrations tend to increase throughout life.
diethylstilbestrol (6898-97-1, 56-53-1, 22610-99-7, 64-67-5)
Stilbestrol · Distilbène · Stilbene Estrogen
trichlorocarbanilide · Cutisan · Septivon
Triclocarban is an antibacterial agent common in personal care products like soaps and lotions as well as in the medical field, for which it was originally developed. Studies on its antibacterial qualities and mechanisms are growing. Research suggests that it is similar in its mechanism to triclosan and is effective in fighting infections by targeting the growth of bacteria such as Staphylococcus aureus.
Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class. It works as an insulin sensitizer, by binding to the PPAR in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug or for use in combination with metformin or with glimepiride.
digitoxin (8006-96-0, 71-63-6, 87112-48-9)
Digitaline Nativelle · corax Brand of Digitoxin · Chauvin Brand of Digitoxin
Digitoxin is a cardiac glycoside. It is a phytosteroid and is similar in structure and effects to digoxin (though the effects are longer-lasting). Unlike digoxin (which is eliminated from the body via the kidneys), it is eliminated via the liver, so could be used in patients with poor or erratic kidney function.
kempferol · 3,4',5,7-tetrahydroxyflavone
Kaempferol is a natural flavonol, a type of flavonoid, found in a variety of plants and plant-derived foods. Kaempferol is a yellow crystalline solid with a melting point of 276–278 °C (529–532 °F). It is slightly soluble in water and highly soluble in hot ethanol, ethers, and DMSO.
Lotrimin · Mycelex · Canesten
Clotrimazole, sold under the brand name Canesten among others, is an antifungal medication. It is used to treat vaginal yeast infections, oral thrush, diaper rash, pityriasis versicolor, and types of ringworm including athlete's foot and jock itch. It can be taken by mouth or applied as a cream to the skin or in the vagina.
4-HYDROXYBENZOIC ACID (99-96-7)
4-hydroxybenzoic acid, calcium salt · sodium p-hydroxybenzoate tetrahydrate · 4-hydroxybenzoic acid, dipotassium salt
4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a monohydroxybenzoic acid, a phenolic derivative of benzoic acid. It is a white crystalline solid that is slightly soluble in water and chloroform but more soluble in polar organic solvents such as alcohols and acetone. 4-Hydroxybenzoic acid is primarily known as the basis for the preparation of its esters, known as parabens, which are used as preservatives in cosmetics and some ophthalmic solutions.
Ethinylestrenol · Linestrenol · Lynestrenol, (9 beta, 10 alpha,17 alpha)-Isomer
Lynestrenol is a progestin which is used in oral contraceptives in combination with an estrogen and in the treatment of gynecological disorders. It is has potent progestogenic effects on the uterine endometrium (transforming proliferative endometrium into secretory one), inhibits secretion of gonadotropins, suppresses maturation of follicles in the ovaries and ovulation, and reduces menstrual bleeding.
hydroxyprogesterone (604-09-1, 68-96-2)
17 Hydroxyprogesterone · 17 alpha Hydroxyprogesterone · 17 alpha-Hydroxyprogesterone
Hydroxyprogesterone (OHP) may refer to: 3α-Hydroxyprogesterone (3α-dihydroprogesterone) 3β-Hydroxyprogesterone (3β-dihydroprogesterone) 11α-Hydroxyprogesterone 11β-Hydroxyprogesterone (21-deoxycorticosterone) 16α-Hydroxyprogesterone 17α-Hydroxyprogesterone 20α-Hydroxyprogesterone 21-Hydroxyprogesterone (11-deoxycorticosterone)
trans-Anethole (4180-23-8, 85681-56-7, 50770-19-9, 104-46-1)
anethole · 1-methoxy-4-(1-propenyl)benzene · p-propenylanisole
Anethole (anise camphor) is an organic compound that is widely used as a flavoring substance. It is a derivative of phenylpropene, a type of aromatic compound that occurs widely in nature, in essential oils. It contributes a large component of the odor and flavor of anise and fennel (both in the botanical family Apiaceae), anise myrtle (Myrtaceae), liquorice (Fabaceae), camphor, magnolia blossoms, and star anise (Illiciaceae).
bis(4-hydroxyphenyl)sulfone · bisphenol S
Bisphenol S (BPS) is an organic compound with the formula (HOC6H4)2SO2. It has two phenol functional groups on either side of a sulfonyl group. It is commonly used in curing fast-drying epoxy resin adhesives.
pHisoHex · Irgasan DP300 · Irgasan DP 300
Triclosan (sometimes abbreviated as TCS), similar in its uses and mechanism of action to triclocarban, is an antibacterial and antifungal agent found in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remain controversial. Additional research seeks to understand its potential effects on organisms and environmental health.
Eulexin · Euflex · SCH 13521
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. It is also used in the treatment of androgen-dependent conditions like acne, excessive hair growth, and high androgen levels in women. It is taken by mouth, usually three times per day.
2-Methoxyestradiol (2-ME2) is a natural metabolite of estradiol. As an experimental drug candidate, it is being developed under the tradename of Panzem. It prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis), hence it is an angiogenesis inhibitor.
Bifon · Mycospor · Bay H 4502
Bifonazole (trade name Canespor among many others) is an imidazole antifungal drug used in form of ointments. There are also combinations with carbamide for the treatment of onychomycosis.
Hydroxytyrosol is a phenylethanoid, a type of phenolic phytochemical with antioxidant properties in vitro. In nature, hydroxytyrosol is found in olive leaf and olive oil, in the form of its elenolic acid ester oleuropein and, especially after degradation, in its plain form. Hydroxytyrosol itself in pure form is a colorless, odorless liquid.