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Alcohols, Drugs acting on the cardiovascular system

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Antiarrhythmic agents (38)
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BISOPROLOL (66722-44-9)  
Concor  ·  Bisoprolol Fumarate  ·  EMD-33512
Bisoprolol, marketed under the tradename Zebeta among others, is a medication most commonly used for heart diseases. This specifically includes high blood pressure, chest pain from not enough blood flow to the heart, and heart failure. It is taken by mouth.
Ibutilide (122647-32-9, 122647-31-8)  
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period (physiology) of myocardial cells. Because of its Class III antiarrhythmic activity, there should not be concomitant administration of Class Ia and Class III agents.
acebutolol (37517-30-9)  
Prent  ·  Sectral  ·  Acebutolol Hydrochloride
Acebutolol (trade names Sectral, Prent) is a beta blocker for the treatment of hypertension and arrhythmias.
Salbutamol (18559-94-9)  
Albuterol  ·  Ventolin  ·  Proventil
Salbutamol, also known as albuterol and marketed as Ventolin among other names, is a medication that opens up the medium and large airways in the lungs. It is used to treat asthma including asthma attacks, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease (COPD). It may also be used to treat high blood potassium levels.
buprenorphine (52485-79-7)  
Buprenex  ·  Buprenorphine Hydrochloride  ·  Subutex
Buprenorphine, sold under the brand name Subutex, among others, is an opioid used to treat opioid addiction, acute pain, and chronic pain. It can be used under the tongue, by injection, as a skin patch, or as an implant. When used for opioid addiction it is recommended that a health care provider observe the person while they take the medication.
ISOSORBIDE MONONITRATE (16051-77-7)  
Ismo  ·  Imdur  ·  Monoket
Isosorbide mononitrate is a drug used principally in the treatment of angina pectoris and acts by dilating the blood vessels so as to reduce the blood pressure. It is sold in the USA by Kremers Urban under the trade name Monoket, also sold in the USA under the name Imdur, and marketed in the UK under the trade names: Isotard, Monosorb, Chemydur. In India, this drug is available under the brand names of Ismo, Isonorm, Monotrate, Solotrate, and Monit.
betaxolol (63659-18-7)  
Betoptic  ·  Kerlone  ·  Betaxolol Hydrochloride
Betaxolol (trade names Betoptic, Betoptic S, Lokren, Kerlone) is a selective beta1 receptor blocker used in the treatment of hypertension and glaucoma. Being selective for beta1 receptors, it typically has fewer systemic side effects than non-selective beta-blockers, for example, not causing bronchospasm (mediated by beta2 receptors) as timolol may. Betaxolol also shows greater affininty for beta1 receptors than metoprolol.
nylidrin (447-41-6)  
Arlidin  ·  Nylidrin Hydrochloride  ·  Dilatol
Buphenine (or nylidrin) is a β2 adrenoreceptor agonist that acts as a vasodilator.
LEVOBUNOLOL (47141-42-4)  
Levobunolol (AK-Beta, Liquifilm, Betegan) is a non-selective beta blocker. It is used topically to manage glaucoma.
CARTEOLOL (51781-06-7)  
Carteolol Hydrochloride  ·  OPC1085  ·  OPC 1085
Carteolol (trade names Cartrol, Ocupress, Teoptic, Arteolol, Arteoptic, Calte, Cartéabak, Carteol, Cartéol, Cartrol, Elebloc, Endak, Glauteolol, Mikelan, Poenglaucol, Singlauc) is a non-selective beta blocker used to treat glaucoma. It has been found to act as a serotonin 5-HT1A and 5-HT1B receptor antagonist in addition to being a beta blocker.
alprenolol (13655-52-2)  
Aptin  ·  Alpheprol  ·  Alprenolol Hydrochloride
Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist, used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.
cyclandelate (456-59-7)  
Cyclospasmol
Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine. It is orally administered.
Levalbuterol (18559-94-9, 34391-04-3)  
Levosalbutamol, also known as levalbuterol, is a short-acting β2 adrenergic receptor agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Evidence does not show that levosalbutamol works better than salbutamol, thus there may not be sufficient justification for prescribing it. The drug is the (R)-(−)-enantiomer of its prototype drug salbutamol.
celiprolol (56980-93-9)  
Selectol  ·  Celiprolol, Monohydrochloride, (R)-Isomer  ·  Celiprolol Monohydrochloride
Celiprolol (brand names Cardem, Selectol, Celipres, Celipro, Celol, Cordiax, Dilanorm) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It has a unique pharmacology: it is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is also a weak α2 receptor antagonist.
Ajmaline (4360-12-7)  
Wolfina  ·  Ajmaline Hydrochloride  ·  Aritmina
Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is class Ia antiarrhythmic agent. It is often used to bring out typical findings of ST elevations in patients suspected of having Brugada syndrome. The compound was first isolated by Salimuzzaman Siddiqui in 1931 from the roots of Rauwolfia serpentina.
CHEBI:28462 (4360-12-7)  
Ajmaline (also known by trade names Gilurytmal, Ritmos, and Aritmina) is an alkaloid that is class Ia antiarrhythmic agent. It is often used to bring out typical findings of ST elevations in patients suspected of having Brugada syndrome. The compound was first isolated by Salimuzzaman Siddiqui in 1931 from the roots of Rauwolfia serpentina.
BUPRANOLOL (23284-25-5, 14556-46-8)  
KL-255  ·  Betadrenol  ·  KL 255
Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol.
Bevantolol (59170-23-9)  
bevantolol hydrochloride  ·  CI 775  ·  CI-775
Bevantolol (INN) was a drug candidate for angina and hypertension that acted as both a beta blocker and a calcium channel blocker. It was discovered and developed by Warner-Lambert but in January 1989 the company announced that it had withdrawn the New Drug Application; the company's chairman said: "Who needs the 30th beta blocker?" As of 2016 it wasn't marketed in the US, UK, or Europe and the authors of a Cochrane review could find no product monograph for it.
Ifenprodil (23210-56-2, 23210-58-4)  
4-benzyl-alpha-(p-hydroxyphenyl)-beta-methyl-1-piperidineethanol  ·  ifenprodil tartrate (2:1), (R-(R*,R*))-isomer  ·  ifenprodil, (R*,S*)-(+-)-isomer
Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 (glycine-binding NMDA receptor subunit 1) and GluN2B (glutamate-binding NMDA receptor subunit 2) subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors. NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits.
Etilefrine (709-55-7, 10128-36-6)  
Thomasin  ·  Etilefrine Hydrochloride  ·  Phetanol
Etilefrine is a cardiac stimulant used as an antihypotensive. It is a sympathomimetic amine of the 3-hydroxy-phenylethanolamine series used in treating orthostatic hypotension of neurological, cardiovascular, endocrine or metabolic origin. Intravenous infusion of this compound increases cardiac output, stroke volume, venous return and blood pressure in man and experimental animals, suggesting stimulation of both α and β adrenergic receptors.
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