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Alkaloids, Drugs acting on the cardiovascular system

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Antiarrhythmic agents (14)
Drugs acting on the nervous system (10)
Psychoactive drugs (10)
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Alkaloids found in Iboga (1)
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papaverine (61-25-6, 58-74-2)  
Papaverine Hydrochloride  ·  Pavabid  ·  Cerespan
Papaverine (Latin papaver, "poppy") is an opium alkaloid antispasmodic drug, used primarily in the treatment of visceral spasm, vasospasm (especially those involving the intestines, heart, or brain), and occasionally in the treatment of erectile dysfunction. It is used in the treatment of acute mesenteric ischemia. While it is found in the opium poppy, papaverine differs in both structure and pharmacological action from the analgesic (morphine-related) opium alkaloids (opiates).
Cathinone (71031-15-7)  
Cathinone (also known as benzoylethanamine, or β-keto-amphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat) and is chemically similar to ephedrine, cathine, methcathinone and other amphetamines. It is probably the main contributor to the stimulant effect of Catha edulis. Cathinone differs from many other amphetamines in that it has a ketone functional group.
(+)-Sparteine (492-08-0, 90-39-1)  
Sparteine  ·  Sparteine Sulfate  ·  Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalent cations calcium and magnesium.
SAXITOXIN (73603-72-2, 35523-89-8)  
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the human illness known as paralytic shellfish poisoning (PSP). The term saxitoxin originates from the genus name of the butter clam (Saxidomus) from which it was first isolated.
Sparteine (90-39-1)  
Sparteine Sulfate  ·  Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer  ·  Sparteine Sulfate Anhydrous
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalent cations calcium and magnesium.
beta-Isosparteine (24915-04-6, 90-39-1, 446-95-7)  
Sparteine  ·  Sparteine Sulfate  ·  Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalent cations calcium and magnesium.
lupinidine (90-39-1)  
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalent cations calcium and magnesium.
Genisteine (90-39-1)  
Sparteine  ·  Sparteine Sulfate  ·  Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Dauricine (524-17-4)  
Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid. It has been isolated from the Asian vine Menispermum dauricum, commonly known as Asian moonseed, and the North American vine Menispermum canadense, commonly known as Canadian moonseed. Scientists Tetsuji Kametani and Keiichiro Fukumoto of Japan are credited with being the first to synthesize dauricine in 1964, using both the Arndt-Eistert reaction and Bischler-Napieralski reaction to do so.
racanisodamine (55869-99-3)  
anisodamine  ·  anisodamine hydrobromide  ·  6-hydroxyhyoscyamine
Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt. Eye drops at 0.5% concentration for slowing the progression is also available in China.
anisodamine (55869-99-3)  
Anisodamine, also known as 7β-hydroxyhyoscyamine, is an anticholinergic and α1 adrenergic receptor antagonist used in the treatment of acute circulatory shock in China. It is given orally or by injection, as a racemic mixture (racanisodamine) or as a hydrobromide salt. Eye drops at 0.5% concentration for slowing the progression is also available in China.
Canadine (5096-57-1, 522-97-4, 29074-38-2)  
tetrahydroberberine  ·  canadine, (+-)-isomer  ·  canadine hydrochloride
Canadine is a protoberberine alkaloid which can act as a calcium channel blocker. It is also one of the many alkaloids found in Corydalis yanhusuo from the family of Papaveraceae.
Ergine (478-94-4)  
lysergic acid amide  ·  lysergamide  ·  9,10-didehydro-6-methylergoline-8 beta-carboxamide
Ergine, also known as d-lysergic acid amide (LSA) and d-lysergamide, is an alkaloid of the ergoline family that occurs in various species of vines of the Convolvulaceae and some species of fungi. As the dominant alkaloid in the psychedelic seeds of Turbina corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian baby woodrose) and Ipomoea tricolor (morning glories, tlitliltzin, Badoh negro), it is often stated that ergine and/or isoergine (its epimer) is responsible for the psychedelic activity. However, this theory is debatable, as anecdotal reports suggest that the effects of synthetic LSA and iso-LSA are only slightly psychedelic, see Mixing the Kykeon below for a summary of human trials, and Chapter 17 and entry #26 of TiHKAL for further discussion.
CORONARIDINE (467-77-6)  
coronardine monohydrochloride  ·  coronardine monohydrochloride, (+-)-isomer  ·  coronardine
Canadine l-form (5096-57-1)  
Canadine is a protoberberine alkaloid which can act as a calcium channel blocker. It is also one of the many alkaloids found in Corydalis yanhusuo from the family of Papaveraceae.
anisodine (52646-92-1)  
Anisodine, also known as daturamine and α-hydroxyscopolamine, is an antispasmodic and anticholinergic drug used in the treatment of acute circulatory shock in China. It is a tropane alkaloid and is found naturally in species of the Solanaceae family of plants. Anisodine acts as a muscarinic acetylcholine receptor antagonist and α1-adrenergic receptor agonist.
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