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Alkaloids, Heterocyclic compounds


Cyclic compounds (12)
Heterocyclic compounds (4 or more rings) (7)
Polycyclic organic compounds (7)
Drugs acting on the nervous system (6)
Psychoactive drugs (4)
Alkaloid (3)
Analgesics (3)
Kappa agonists (3)
Opioid receptor ligands (3)
Opioids (3)
Heterocyclic compound (2)
Heterocyclic compounds (3 rings) (2)
Ketones (2)
Nervous system drug (2)
Heterocyclic compounds (2 rings) (1)
Natural opium alkaloids (1)
Opium (1)
Quaternary ammonium compounds (1)
Quaternary compounds (1)


Sigma Aldrich (2)
Frontier Scientific (1)
Oakwood Chemical (1)
TCI Chemicals (1)

protopine (130-86-9)  
fumarine  ·  protopine mesylate  ·  4,6,7,14-tetrahydro-5-methyl-bis(1,3)benzodioxolo(4,5-c-5',6'-g)azecin-13(5H)-one
Protopine is a benzylisoquinoline alkaloid occurring in opium poppy, Corydalis tubers and other plants of the family papaveraceae, like Fumaria officinalis. It has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic.
Matrine (519-02-8)  
Matrine is an alkaloid found in plants from the Sophora genus. It has a variety of pharmacological effects, including anti-cancer effects, as well as κ-opioid and μ-opioid receptor agonism. Matrine possesses strong antitumor activities in vitro and in vivo.
9-Methyl-9-azabicyclo[3.3.1]nonan-3-one (552-70-5)  
Pseudopelletierine is the main alkaloid derived from the root-bark of the pomegranate tree (Punica granatum), along with at least three other alkaloids: pelletierine, isopelletierine, and methylpelleteirine (C9H17ON), which yield 1.8, 0.52, 0.01, and 0.20 grams per kilogram of raw bark. Isopelletierine is optically inactive. It is a homolog of tropinone, and can be synthesized in a manner analogous to the classical Robinson tropinone synthesis, using glutaraldehyde (rather than succinaldehyde), acetonedicarboxylic acid, and methylammonium chloride.
Bulbocapnine (632-47-3, 298-45-3)  
Bulbocapnine is an alkaloid found in Corydalis (Papaveraceae) and Dicentra, plants in the family Fumariaceae that can cause fatal poisoning in sheep and cattle. It has been shown to act as an acetylcholinesterase inhibitor, and inhibits biosynthesis of dopamine via inhibition of the enzyme tyrosine hydroxylase. According to the Dorlands Medical Dictionary, it "inhibits the reflex and motor activities of striated muscle.
EVOXINE (522-11-2)  
Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides and Teclea gerrardii.
Narcotoline (521-40-4)  
narcotoline hydrochloride
Narcotoline is an opiate alkaloid chemically related to noscapine. It binds to the same receptors in the brain as noscapine to act as an antitussive, and has also been used in tissue culture media.
Hasubanonine (1805-85-2)  
Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C21H27NO5. The enantiomer of the natural product is being studied as a potential painkiller.
Rhoeadine (2718-25-4)  
Rhoeadine (rheadine) is an alkaloid derived from the flowers of the corn poppy (Papaver rhoeas). It is used as mild sedative and mild antitussive. It has been studied and shown promise in the treatment of morphine dependence.
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