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Alkaloids, PDE4 inhibitors


Antiasthmatic drugs (4)
Antitussives (4)
Drugs acting on the respiratory system (4)
Respiratory agents (4)
Consumer Ingredients (1)

Glaucine (475-81-0)  
glaucine phosphate (5:7), (+-)-isomer  ·  glaucine acetate, (+-)-isomer  ·  glaucine phosphate (2:3), (S)-isomer
Glaucine is an alkaloid found in several different plant species in the Papaveraceae family such as Glaucium flavum, Glaucium oxylobum and Corydalis yanhusuo, and in other plants like Croton lechleri in the family Euphorbiaceae. It has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. Glaucine may produce side effects such as sedation, fatigue, and a hallucinogenic effect characterised by colourful visual images, and has been detected as a novel psychoactive drug.
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