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Antiarrhythmic agents, Antitussives


Drugs acting on the cardiovascular system (8)
Drugs acting on the respiratory system (8)
Potassium channel blockers (8)
Respiratory system drug (8)
Drugs acting on the nervous system (7)
Psychoactive drugs (6)
Amines (4)
Analgesics (4)
Bases (chemistry) (4)
Euphoriants (4)
Mu-opioid agonists (4)
Opioid receptor ligands (4)
Opioids (4)
Synthetic opioids (4)
Cyclic compounds (3)
Piperidines (3)
Six-membered rings (3)
Antihistamines (2)
Aromatic compounds (2)
Chloroarenes (2)
Ethers (2)
H1 receptor antagonists (2)
Pharmaceuticals (2)
Decongestants (1)
Expectorants (1)
Five-membered rings (1)
Nervous system drug (1)
Thiophenes (1)


Sigma Aldrich (1)

Dextropropoxyphene (469-62-5, 2621-61-6, 2338-37-6)  
Propoxyphene  ·  Darvon  ·  Propoxyphene Hydrochloride
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects.
Levopropoxyphene (2338-37-6)  
Levopropoxyphene is an antitussive. It is an optical isomer of dextropropoxyphene. The racemic mixture is called propoxyphene.
cloperastine (3703-76-2)  
1-(2-((4-chloro-alpha-phenylbenzyl)oxy)ethyl)piperidine  ·  cloperastine hydrochloride
Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. It was first introduced in 1972 in Japan, and then in Italy in 1981. The precise mechanism of action of cloperastine is not fully clear, but several different biological activities have been identified for the drug, of which include: ligand of the σ1 receptor (Ki = 20 nM) (likely an agonist), GIRK channel blocker (described as "potent"), antihistamine (Ki = 3.8 nM for the H1 receptor), and anticholinergic.
Tipepidine (5169-78-8)  
Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate (JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class. It acts as an inhibitor of G protein-coupled inwardly-rectifying potassium channels (GIRKs). The drug was discovered in the 1950s, and was developed in Japan in 1959.
Caramiphen (77-22-5)  
Caramiphen is an anticholinergic drug used in the treatment of Parkinson's disease. In combination with phenylpropanolamine it is used as a cough suppressant and nasal decongestant to treat symptoms associated with respiratory illnesses such as cold, allergies, hay fever, and sinusitis.
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Antiarrhythmic agents