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Antidepressants (9)
Antipsychotics (9)
Anxiolytics (9)
Cyclic compounds (9)
Drugs acting on the nervous system (9)
Psychoactive drugs (9)
Psychopharmacology (9)
Cycloalkanes (6)
Cyclopentanes (6)
Five-membered rings (6)
Piperazines (4)
Six-membered rings (4)
Nervous system drug (3)
Pyrimidines (3)
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Aromatic compounds (1)
Benzodioxins (1)
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Psychoanaleptics (1)
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Triazines (1)
Ureas (1)


SynQuest Laboratories (2)
Sigma Aldrich (2)
Accela (1)
AK Scientific (1)
Apollo Scientific (1)
Oakwood Chemical (1)
TCI Chemicals (1)

3,3-Tetramethyleneglutarimide (1075-89-4)  
Azaspirodecanedione is a chemical compound. It is a component of the chemical structures of several of the azapirones.
Tandospirone (87760-53-0)  
Tandospirone (brand name Sediel) is an anxiolytic and antidepressant drug used in China and Japan, where it is marketed by Dainippon Sumitomo Pharma. It is a member of the azapirone class of drugs and is closely related to other azapirones like buspirone and gepirone.
Eptapirone (179756-85-5)  
Eptapirone (F-11,440) is a very potent and highly selective 5-HT1A receptor full agonist of the azapirone family. Its affinity for the 5-HT1A receptor was reported to be 4.8 nM (Ki) (or 8.33 (pKi)), and its intrinsic activity approximately equal to that of serotonin (i.e., 100%). Eptapirone and related high-efficacy 5-HT1A full and super agonists such as befiradol and F-15,599 were developed under the hypothesis that the maximum exploitable therapeutic benefits of 5-HT1A receptor agonists might not be able to be seen without the drugs employed possessing sufficiently high intrinsic activity at the receptor.
IPSAPIRONE (95847-70-4)  
Ipsapirone is a selective 5-HT1A receptor partial agonist of the piperazine and azapirone chemical classes. It has antidepressant and anxiolytic effects. Ipsapirone was studied in several placebo-controlled trials for depression and continues to be used in research.
Binospirone (102908-59-8)  
Binospirone (MDL-73,005-EF) is a drug which acts as a partial agonist at 5-HT1A somatodendritic autoreceptors but as an antagonist at postsynaptic 5-HT1A receptors. It has anxiolytic effects.
Umespirone (107736-98-1)  
Umespirone (KC-9172) is a drug of the azapirone class which possesses anxiolytic and antipsychotic properties. It behaves as a 5-HT1A receptor partial agonist (Ki = 15 nM), D2 receptor partial agonist (Ki = 23 nM), and α1-adrenoceptor receptor antagonist (Ki = 14 nM), and also has weak affinity for the sigma receptor (Ki = 558 nM). Unlike many other anxiolytics and antipsychotics, umespirone produces minimal sedation, cognitive/memory impairment, catalepsy, and extrapyramidal symptoms.
8-Azaspiro[4.5]decane (176-64-7)  
Azaspirodecane is a chemical compound. It is the core structure of the azaspirodecanedione moiety found in some of the azapirones.