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Barbiturates

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pentobarbital (76-74-4, 57-33-0)  
Nembutal  ·  Pentobarbital Sodium  ·  Pentobarbitone
Pentobarbital (INN, AAN, BAN, USAN) or pentobarbitone (former AAN and BAN) is a short-acting barbiturate. Pentobarbital can occur as both a free acid and as salts of elements such as sodium and calcium. The free acid is only slightly soluble in water and ethanol.
phenobarbital (50-06-6)  
Luminal  ·  Phenobarbitone  ·  Phenobarbital Sodium
Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended by the World Health Organization for the treatment of certain types of epilepsy in developing countries. In the developed world it is commonly used to treat seizures in young children, while other medications are generally used in older children and adults. It may be used intravenously, injected into a muscle, or taken by mouth.
secobarbital (309-43-3, 29071-21-4, 76-73-3)  
Seconal  ·  Secobarbital Sodium  ·  Quinalbarbitone
Secobarbital sodium (marketed by Eli Lilly and Company, and subsequently by other companies as described below, under the brand name Seconal) is a barbiturate derivative drug that was patented in 1934 in the United States. It possesses anaesthetic, anticonvulsant, anxiolytic, sedative, and hypnotic properties. In the United Kingdom, it was known as quinalbarbitone.
amobarbital (57-43-2)  
Amytal  ·  Sodium Amytal  ·  Amylobarbitone
Amobarbital (formerly known as amylobarbitone or sodium amytal) is a drug that is a barbiturate derivative. It has sedative-hypnotic properties. It is a white crystalline powder with no odor and a slightly bitter taste.
Mephobarbital (115-38-8)  
Mebaral  ·  Methylphenobarbital  ·  Methylphenobarbitone
Methylphenobarbital (INN), also known as mephobarbital (USAN, JAN) and mephobarbitone (BAN), marketed under brand names such as Mebaral, Mephyltaletten, Phemiton, and Prominal, is a drug which is a barbiturate derivative and is used primarily as an anticonvulsant, but also as a sedative and anxiolytic. It is the N-methylated analogue of phenobarbital and has similar indications, therapeutic value, and tolerability.
butabarbital (125-40-6)  
Butisol  ·  butabarbital sodium  ·  Butisol Sodium
Butabarbital (trade name Butisol) is a prescription barbiturate sleep aid. Butabarbital has a particularly fast onset of effects and short duration of action compared to other barbiturates, which makes it useful for certain applications such as treating severe insomnia and relieving anxiety before surgical procedures; however it is also relatively dangerous particularly when combined with alcohol, and so is now rarely used, although it is still prescribed in some Eastern European and South American countries. Its intermediate duration of action gives butabarbital an abuse potential slightly lower than secobarbital.
butalbital (77-26-9)  
allylbarbital  ·  butalbital, monosodium salt
Butalbital is a barbiturate with an intermediate duration of action. Butalbital is often combined with other medications, such as acetaminophen (paracetamol) or aspirin, and is commonly prescribed for the treatment of pain and headache. The various formulations combined with codeine are FDA-approved for the treatment of tension headaches.
primidone (125-33-7)  
Mysoline  ·  Sertan  ·  AstraZeneca Brand of Primidone
Primidone (INN, BAN, USP) is an anticonvulsant of the barbiturate class. It is a structural analog of phenobarbital and related to barbiturate-derivative anticonvulsants. The active metabolites, phenobarbital, p-hydroxyphenobarbital, and phenylethylmalonamide, are also anticonvulsants.
TALBUTAL (115-44-6)  
allyl-sec-butyl-barbituric acid  ·  5-allyl-5-sec-butylbarbituric acid
Talbutal (Lotusate) is a barbiturate with a short to intermediate duration of action. It is a structural isomer of butalbital. Talbutal is a schedule III drug in the U.S.
APROBARBITAL (77-02-1)  
allylpropymal, monosodium salt  ·  allylpropymal  ·  aprobarbitone
Aprobarbital (or aprobarbitone), sold as Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic and anticonvulsant properties, and was used primarily for the treatment of insomnia. Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed as it has been replaced by newer drugs with a better safety margin.
metharbital (50-11-3)  
metharbitone  ·  endiemal  ·  methobarbitone
Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy.
Hexobarbital (56-29-1)  
Hexenal  ·  Evipan  ·  Hexobarbitone
Hexobarbital or hexobarbitone, sold both in acid and sodium salt forms as Citopan, Evipan, and Tobinal, is a barbiturate derivative having hypnotic and sedative effects. It was used in the 1940s and 1950s as an agent for inducing anesthesia for surgery, as well as a rapid-acting, short-lasting hypnotic for general use, and has a relatively fast onset of effects and short duration of action. It was also used to murder women prisoners at Ravensbruck Concentration Camp.
Butethal (77-28-1)  
butobarbitone  ·  Soneryl  ·  butobarbital
Butobarbital, also called butobarbitone or butethal, Soneryl, and Neonal, is a hypnotic drug which is a barbiturate derivative. It was developed by Poulenc Brothers (now part of Rhône Poulenc) in 1921.
Heptabarbital (509-86-4)  
Medomin  ·  heptabarbitone  ·  heptabarb
Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family. It was used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.
barbital (57-44-3, 144-02-5)  
Veronal  ·  Barbitone  ·  Medinal
Barbital (or barbitone), marketed under the brand names Veronal for the pure acid and Medinal for the sodium salt, was the first commercially available barbiturate. It was used as a sleeping aid (hypnotic) from 1903 until the mid-1950s. The chemical names for barbital are diethylmalonyl urea or diethylbarbituric acid; hence, the sodium salt (known as medinal, a genericised trademark in the United Kingdom) is known also as sodium diethylbarbiturate.
thiamylal (77-27-0)  
Surital  ·  Thiamylal Sodium  ·  Thioquinalbarbitone
Thiamylal (Surital) is a barbiturate derivative invented in the 1950s. It has sedative, anticonvulsant, and hypnotic effects, and is used as a strong but short acting sedative. Thiamylal is still in current use, primarily for induction in surgical anaesthesia or as an anticonvulsant to counteract side effects from other anaesthetics.
METHOHEXITAL (309-36-4, 151-83-7)  
Brevital  ·  Methohexitone  ·  Methohexital Sodium
Methohexital or methohexitone (marketed under the brand names Brevital and Brietal) is a drug which is a barbiturate derivative. It is classified as short-acting, and has a rapid onset of action. It is similar in its effects to sodium thiopental, a drug with which it competed in the market for anaesthetics.
ALLOBARBITAL (52-43-7)  
diallylbarbituric acid  ·  diallyl barbituric acid  ·  allobarbitone
Allobarbital, also known as allobarbitone and branded as Cibalgine or Dial-Ciba (in combination with ethyl carbamate), is a barbiturate derivative invented in 1912 by Ernst Preiswerk and Ernst Grether working for CIBA. It was used primarily as an anticonvulsant although it has now largely been replaced by newer drugs with improved safety profiles. Other uses for allobarbital included as an adjutant to boost the activity of analgesic drugs, and use in the treatment of insomnia and anxiety.
CYCLOBARBITAL (52-31-3, 143-76-0)  
cyclobarbitone  ·  hexemal  ·  tetrahydrophenobarbital
Cyclobarbital, also known as cyclobarbitol or cyclobarbitone, is a drug which is a barbiturate derivative. It is primarily available in fixed-dose combination with diazepam under the brand name Reladorm (100 mg cyclobarbital + 10 mg diazepam) and is used to treat insomnia in Russia.
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