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Carboxylic acids, Antihypertensive agents

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Acids (20)
Drugs acting on the cardiovascular system (20)
Organic acids (20)
Cyclic compounds (19)
Agents acting on the renin-angiotensin system (13)
ACE inhibitors (12)
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Amines (3)
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Antiarrhythmic agents (3)
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Calcium channel blockers (3)
Thiazolidines (3)
Angiotensin II receptor antagonists (1)
Antihypertensive agent (1)
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Cyclopentanes (1)
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captopril (62571-86-2)  
Capoten  ·  SQ 14225  ·  SQ 14,225
Captopril, sold under the trade name Capoten, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was discovered in 1977. It was the first ACE inhibitor developed and was considered a breakthrough both because of its novel mechanism of action and also because of the revolutionary development process.
lisinopril (77726-95-5, 76547-98-3, 83915-83-7)  
Zestril  ·  Prinivil  ·  MK-521
Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class used primarily in treatment of high blood pressure, heart failure, and after heart attacks. It is also used for preventing kidney and eye complications in people with diabetes. Its indications, contraindications, and side effects are as those for all ACE inhibitors.
baclofen (62594-36-9, 1134-47-0)  
Lioresal  ·  Genpharm  ·  beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat spasticity. It is used as a central nervous system depressant and skeletal muscle relaxant although its effectiveness has not been clearly shown. It is also used in topical creams to help with pain.
cilazapril (92077-78-6, 88768-40-5)  
Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. It is branded as Dynorm, Inhibace, Vascace and many other names in various countries. None of these are available in the United States as of May 2010.
(R)-Baclofen (69308-37-8)  
Arbaclofen placarbil ( ar-BAK-loh-fen plÉ™-KAR-bil, also known as XP19986) is a prodrug of R-baclofen. Arbaclofen placarbil possesses more favorable pharmacokinetic profile than baclofen, with less fluctuations in plasma drug levels. It was being developed as a potential treatment for patients with GERD and spasticity due to multiple sclerosis; however, in May 2013 XenoPort announced the termination of development because of unsuccessful results in phase III clinical trials.
Omapatrilat (167305-00-2)  
Omapatrilat (INN, proposed trade name Vanlev) is an experimental antihypertensive agent that was never marketed. It inhibits both neprilysin (neutral endopeptidase, NEP) and angiotensin-converting enzyme (ACE). NEP inhibition results in elevated natriuretic peptide levels, promoting natriuresis, diuresis, vasodilation, and reductions in preload and ventricular remodeling.
Rentiapril (80830-42-8)  
Rentiapril is an ACE inhibitor.
Indacrinone (56049-88-8, 57296-63-6)  
indanone  ·  indanone, (+-)-isomer  ·  indanone, (R)-isomer
Indacrinone is a loop diuretic. It can be used in patients of gout with hypertension as an antihypertensive because it decreases reabsorption of uric acid, while other diuretics increase it.
Ozolinone (56784-39-5)  
3-methyl-4-oxo-5-piperidinothiazolidine-2-ylidine acetic acid  ·  ozolinone, (Z)-(-)-isomer  ·  ozolinone, (Z)-(+)-isomer
Ozolinone is a loop diuretic which was never marketed. It is an active metabolite of etozoline.
Abitesartan (137882-98-5)  
Abitesartan (INN) is an Angiotensin II receptor antagonist.
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Carboxylic acids
Antihypertensive agents