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Cardiovascular system drug, Bases (chemistry)

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Drugs acting on the cardiovascular system (34)
Amines (28)
Antihypertensive agents (22)
Antiarrhythmic agents (20)
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Dextropropoxyphene (469-62-5, 2621-61-6, 2338-37-6)  
Propoxyphene  ·  Darvon  ·  Propoxyphene Hydrochloride
Dextropropoxyphene is an analgesic in the opioid category, patented in 1955 and manufactured by Eli Lilly and Company. It is an optical isomer of levopropoxyphene. It is intended to treat mild pain and also has antitussive (cough suppressant) and local anaesthetic effects.
guanabenz (5051-62-7)  
Wytensin  ·  Guanabenz Acetate  ·  BR 750
Guanabenz (pronounced GWAHN-a-benz, sold under the trade name Wytensin) is an alpha agonist of the alpha-2 adrenergic receptor that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension). The most common side effects during guanabenz therapy are dizziness, drowsiness, dry mouth, headache and weakness.
Mibefradil (116644-53-2)  
Mibefradil (Posicor) is a drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers. The mechanism of action of mibefradil is characterized by the selective blockade of transient, low-voltage-activated (T-type) calcium channels over long-lasting, high-voltage-activated (L-type) calcium channels, which is probably responsible for many of its unique properties.
bepridil (64706-54-3)  
Cordium  ·  Vascor  ·  Bepadin
Bepridil (trade name Vascor) is an amine calcium channel blocker once used to treat angina. It is no longer sold in the United States. It is nonselective.
BOPINDOLOL (62658-63-3, 69010-88-4)  
Bopindolol (INN) is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole.
Betanidine (114-85-2, 55-73-2)  
Batel  ·  Bethanidine  ·  Bethanidine Sulfate
Betanidine (or bethanidine) is a sympatholytic drug.
CARTEOLOL (51781-06-7)  
Carteolol Hydrochloride  ·  OPC1085  ·  OPC 1085
Carteolol (trade names Cartrol, Ocupress, Teoptic, Arteolol, Arteoptic, Calte, Cartéabak, Carteol, Cartéol, Cartrol, Elebloc, Endak, Glauteolol, Mikelan, Poenglaucol, Singlauc) is a non-selective beta blocker used to treat glaucoma. It has been found to act as a serotonin 5-HT1A and 5-HT1B receptor antagonist in addition to being a beta blocker.
alprenolol (13655-52-2)  
Aptin  ·  Alpheprol  ·  Alprenolol Hydrochloride
Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as a 5-HT1A and 5-HT1B receptor antagonist, used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.
pargyline (555-57-7)  
Pargyline Hydrochloride
Pargyline (brand name Eutonyl) is an irreversible selective monoamine oxidase (MAO)-B inhibitor drug (IC50 for MAO-A is 0.01152 µmol/L and for MAO-B is 0.00820 µmol/L) It was brought to market in the US and the UK by Abbott in 1963 as an antihypertensive drug branded "Eutonyl". It was one of several MAO inhibitors introduced in the 1960s including nialamide, isocarboxazid, phenelzine, and tranylcypromine. By 2007 the drug was discontinued and as of 2014 there were no generic versions available in the US.
Metipranolol (22664-55-7)  
Trimepranol  ·  Methypranol  ·  Disorat
Metipranolol (OptiPranolol, Betanol, Disorat, Trimepranol) is a non-selective beta blocker used in eye drops to treat glaucoma. It is rapidly metabolized into desacetylmetipranolol.
Debrisoquine (1131-64-2)  
Debrisoquin  ·  Tendor
Debrisoquine is a derivative of guanidine. It is an antihypertensive drug similar to guanethidine. Debrisoquine is frequently used for phenotyping the CYP2D6 enzyme, a drug metabolizing enzyme.
Levopropoxyphene (2338-37-6)  
Levopropoxyphene is an antitussive. It is an optical isomer of dextropropoxyphene. The racemic mixture is called propoxyphene.
APRINDINE (37640-71-4)  
Fiboran  ·  Amidonal
Aprindine is a Class 1b antiarrhythmic agent. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given orally.
Bevantolol (59170-23-9)  
bevantolol hydrochloride  ·  CI 775  ·  CI-775
Bevantolol (INN) was a drug candidate for angina and hypertension that acted as both a beta blocker and a calcium channel blocker. It was discovered and developed by Warner-Lambert but in January 1989 the company announced that it had withdrawn the New Drug Application; the company's chairman said: "Who needs the 30th beta blocker?" As of 2016 it wasn't marketed in the US, UK, or Europe and the authors of a Cochrane review could find no product monograph for it.
fendiline (13042-18-7)  
Sensit  ·  Fendilin  ·  Senzit
Fendiline is a calcium channel blocker. It is nonselective.
Gallopamil (16662-47-8)  
D600  ·  D 600  ·  Procorum
Gallopamil (INN) is an L-type calcium channel blocker that is an analog of verapamil. It is used in the treatment of cardiac arrhythmias.
Hexobendine (54-03-5, 50-62-4)  
Ditrimine  ·  Andiamine  ·  Ustimon
Hexobendine is a vasodilator that acts as an adenosine reuptake inhibitor.
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