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Drugs for acid-related disorders

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Drugs acting on the gastrointestinal system and metabolism (28)
Cyclic compounds (19)
Antihistamines (14)
Drugs acting on the nervous system (14)
H2 receptor antagonists (14)
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ranitidine (68109-63-7, 71130-06-8, 66357-35-5, 66357-59-3)  
Zantac  ·  Ranitidine Hydrochloride  ·  Biotidin
Ranitidine, sold under the trade name Zantac among others, is a medication that decreases stomach acid production. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. There is also tentative evidence of benefit for hives.
CALCIUM CARBONATE (13397-26-7, 1317-65-3, 471-34-1, 13701-58-1, 72608-12-9, 308068-21-5, 13397-25-6, 471-34-1, 7440-70-2)  
Marble  ·  Limestone  ·  Chalk
Calcium carbonate is a chemical compound with the formula CaCO3. It is a common substance found in rocks as the minerals calcite and aragonite (most notably as limestone, which contains both of those minerals) and is the main component of pearls and the shells of marine organisms, snails, and eggs. Calcium carbonate is the active ingredient in agricultural lime and is created when calcium ions in hard water react with carbonate ions to create limescale.
76824-35-6 (76824-35-6)  
Famotidine  ·  Pepcid  ·  MK 208
omeprazole (73590-58-6, 161796-78-7)  
Prilosec  ·  H 168 68  ·  Omeprazole Magnesium
Omeprazole, sold under the brand names Prilosec and Losec among others, is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. It can be taken by mouth or injected into a vein.
Calsil (1344-95-2)  
Calcium silicate is the chemical compound Ca2SiO4, also known as calcium orthosilicate and is sometimes formulated as 2CaO·SiO2. It is also referred to by the shortened trade name Cal-Sil or Calsil.
rabeprazole (117976-89-3)  
Rabeprazole is a proton pump inhibitor used to suppress gastric acid production for a number of medical uses. Rabeprazole is used in the management of conditions that involve excess gastric acid production (e.g. Zollinger-Ellison syndrome), conditions that are worsened by gastric acid (e.g.
MAGNESIUM CARBONATE (7757-69-9, 13717-00-5, 546-93-0)  
magnesite  ·  nesquehonite  ·  MgCO3.3H2O
Magnesium carbonate, MgCO3 (archaic name magnesia alba), is an inorganic salt that is a white solid. Several hydrated and basic forms of magnesium carbonate also exist as minerals.
lansoprazole (103577-45-3)  
Prevacid  ·  TAP Brand of Lansoprazole  ·  Lansoprazole Hormona Brand
Lansoprazole, sold under the brand name Prevacid among others, is a medication which inhibits the stomach's production of acid. There is no evidence that its effectiveness is different from that of other PPIs. Lansoprazole, given through a nasogatric tube, effectively controls pH inside the stomach and is an alternative to intravenous pantoprazole in people who are unable to swallow solid-dose formulations.
Magnesium peroxide (14452-57-4, 1335-26-8)  
Magnesium peroxide (MgO2) is an odorless fine powder peroxide with a white to off-white color. It is similar to calcium peroxide because magnesium peroxide also releases oxygen by breaking down at a controlled rate with water. Commercially, magnesium peroxide often exists as a compound of magnesium peroxide and magnesium hydroxide.
MAGNESIUM HYDROXIDE (1309-42-8)  
Brucite  ·  Magnesium Hydrate  ·  Magnesium Hydroxide (Mg(OH)4)
Magnesium hydroxide is the inorganic compound with the chemical formula Mg(OH)2. It occurs in nature as the mineral brucite. It is a white solid with low solubility in water (Ksp = 5.61×10−12).
ROXATIDINE ACETATE (78628-28-1)  
Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis. Pharmacodynamic studies showed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion. It is available in countries including China, Japan, Korea, Germany, Italy, the Netherlands, Greece and South Africa.
UNII-884KT10YB7 (66357-35-5)  
Ranitidine, sold under the trade name Zantac among others, is a medication that decreases stomach acid production. It is commonly used in treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. There is also tentative evidence of benefit for hives.
Ebrotidine (100981-43-9)  
Ebrotidine is an H2 receptor antagonist with gastroprotective activity against ethanol-, aspirin- or stress-induced gastric mucosal damage. The antisecretory properties of ebrotidine are similar to those of ranitidine, and approximately 10-fold greater than those of cimetidine. Ebrotidine has anti-Helicobacter pylori activity via inhibition of the urease enzyme and the proteolytic and mucolytic activities of the bacterium.
Loxtidine (76956-02-0)  
Lavoltidine (INN, USAN, BAN; previously known as loxtidine, code name AH-23,844) is a highly potent and selective H2 receptor antagonist which was under development by Glaxo Wellcome (now GlaxoSmithKline) as a treatment for gastroesophageal reflux disease but was discontinued due to the discovery that it produced gastric carcinoid tumors in rodents.
Tenatoprazole (113712-98-4, 705969-00-2)  
Tenatoprazole is a proton pump inhibitor drug candidate that was undergoing clinical testing as a potential treatment for reflux oesophagitis and peptic ulcer as far back as 2003. The compound was invented by Mitsubishi Tanabe Pharma and was licensed to Negma Laboratories (part of Wockhardt as of 2007). Mitsubishi reported that tenatoprazole was still in Phase I clinical trials in 2007 and again in 2012.
Zolimidine (1222-57-7)  
Solimidine  ·  Solmidin
Zolimidine (zoliridine, brand name Solimidin) is a gastroprotective drug previously used for peptic ulcer and gastroesophageal reflux disease.
Zolantidine (104076-38-2, 104076-39-3)  
Zolantidine is a brain-penetrating selective histamine H2 receptor (HRH2) antagonist developed by Smith, Kline & French, with the research code of SK&F 95282. It is a benzthiazole derivative with a 30-fold higher potency for H2 receptors than other peripheral and central receptors.
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