Sex hormones (11)
Sigma Aldrich (4)
AK Scientific (1)
Oakwood Chemical (1)
TCI Chemicals (1)
Norethisterone · Micronor · Norlutin
Norethisterone (NET), also known as norethindrone, is a medication that is used in combination with estrogen or alone in hormonal contraceptives, menopausal hormone therapy, and in the treatment of gynecological disorders. It is a synthetic progestogen (or a progestin) of the 19-nortestosterone group and has similar effects to those of natural progesterone, including suppression of gonadotropins, ovulation inhibition, and endometrial transformation. In addition to its progestogenic activity, NET also has weak androgenic and estrogenic effects at high dosages.
Etynodiol, or ethynodiol, is a steroidal progestin of the 19-nortestosterone group which was never marketed. A diacylated derivative, etynodiol diacetate, is used as a hormonal contraceptive. While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate, not etynodiol.
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow.
Teslac · delta(1)-Testolactone · Bristol-Myers Squibb Brand of Testolactone
Testolactone (INN, USAN) (brand name Teslac) is a non-selective, irreversible, steroidal aromatase inhibitor which is used as an antineoplastic drug to treat advanced-stage breast cancer. The drug was discontinued in 2008 and is no longer available for medical use.
Ethinylestrenol · Linestrenol · Lynestrenol, (9 beta, 10 alpha,17 alpha)-Isomer
Lynestrenol is a progestin which is used in oral contraceptives in combination with an estrogen and in the treatment of gynecological disorders. It is has potent progestogenic effects on the uterine endometrium (transforming proliferative endometrium into secretory one), inhibits secretion of gonadotropins, suppresses maturation of follicles in the ovaries and ovulation, and reduces menstrual bleeding.
Medroxyprogesterone acetate (71-58-9)
Provera · DepoProvera · Depo Provera
Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. It is used as birth control and as part of menopausal hormone therapy. It is also used to treat endometriosis, abnormal uterine bleeding, abnormal sexuality in males, and certain types of cancer.
ETHYNODIOL DIACETATE (297-76-7)
Continuin · Femulen · (3 beta, 17 alpha)-19-Norpregn-4-en-20-yne-3,17 diol Diacetate
Etynodiol diacetate, or ethynodiol diacetate, is a progestin of the 19-nortestosterone group which is used in oral contraceptives. It is the 3β,17β-diacetate ester of etynodiol, and acts as a rapidly converted prodrug of norethisterone, with etynodiol occurring as an intermediate. Etynodiol diacetate has weak androgenic activity, and, unlike most progestins but similarly to norethisterone and noretynodrel, also has some estrogenic activity.
Formestane, sold under the brand name Lentaron among others, is a steroidal, selective aromatase inhibitor which is used in the treatment of estrogen receptor-positive breast cancer in postmenopausal women. The drug is not active orally, and is instead available only as an intramuscular depot injection. Because of this, it is no longer popular as many orally active aromatase inhibitors have been identified and introduced.
Atamestane (developmental code name SH-489), also known as metandroden, as well as 1-methylandrosta-1,4-diene-3,17-dione, is a steroidal aromatase inhibitor that was studied in the treatment of cancer. It blocks the production of estrogen in the body. The drug is selective, competitive, and irreversible in its inhibition of aromatase.