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Ketones, Hormonal agents

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Systemic hormonal preparations (14)
Drugs acting on the genito-urinary system (7)
Sex hormones (7)
Alcohols (6)
Estrogens (4)
Genito-urinary system drug (4)
Anti-inflammatory agents (3)
Anti-inflammatory and antirheumatic products (3)
Antineoplastic and immunomodulating drugs (3)
Drugs acting on the musculoskeletal system (3)
Glucocorticoids (3)
Immunomodulating drugs (3)
Immunosuppressants (3)
Mineralocorticoids (3)
Synthetic estrogens (3)
Antiestrogens (2)
Antiglucocorticoids (2)
Pharmaceuticals (2)
Progestogens (2)
Antiandrogens (1)
Antigonadotropins (1)
Aromatic compounds (1)
Aromatic ketones (1)
Corticosteroid cyclic ketals (1)
Cyclic compounds (1)
Drugs for benign prostatic hyperplasia (1)
Halides (1)
Organobromides (1)
Organohalides (1)
Piperidines (1)
Selective estrogen receptor modulators (1)
Six-membered rings (1)
Urologicals (1)

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Toronto Research Chemicals (2)
Matrix Scientific (1)
Sigma Aldrich (1)

raloxifene (84449-90-1)  
Raloxifene, sold under the brand name Evista among others, is a medication which is used in the prevention and treatment of osteoporosis in postmenopausal women and to reduce the risk of breast cancer in postmenopausal women with osteoporosis or at high risk for breast cancer. It is taken by mouth. Side effects of raloxifene include hot flashes, leg cramps, and an increased risk of blood clots and other cardiovascular events such as stroke.
Omnaris HFA (126544-47-6, 141845-82-1)  
Ciclesonide is a glucocorticoid used to treat asthma and allergic rhinitis. It is marketed under the brand names Alvesco for asthma and Omnaris, Omniair, and Zetonna for hay fever in the US and Canada. Phase 3 trials for the hay fever indication outside the US are ongoing.
16alpha-Hydroxyestrone (566-76-7)  
16α-Hydroxyestrone (16α-OH-E1), or hydroxyestrone, also known as estra-1,3,5(10)-trien-3,16α-diol-17-one, is an endogenous steroidal estrogen and a major metabolite of estrone, as well as an intermediate in the biosynthesis of estriol. It is a potent estrogen similarly to estrone, and it has been suggested that the ratio of 16α-hydroxyestrone to 2-hydroxyestrone, the latter being much less estrogenic in comparison and even antiestrogenic in the presence of more potent estrogens like estradiol, may be involved in the pathophysiology of breast cancer. Conversely, 16α-hydroxyestrone may help to protect against osteoporosis.
53-00-9 (53-00-9)  
7α-Hydroxydehydroepiandrosterone (7α-hydroxy-DHEA; 7α-OH-DHEA), also known as 3β,7α-dihydroxyandrost-4-ene-17-one, is an endogenous, naturally occurring steroid and a major metabolite of dehydroepiandrosterone (DHEA) that is formed by CYP7B1 (steroid 7α-hydroxylase) in tissues such as the prostate gland and by CYP3A4 in the liver. The major metabolic pathway of DHEA outside the liver is via 7-hydroxylation into 7α-OH-DHEA and 7β-OH-DHEA. 7α-OH-DHEA has weak estrogenic activity, selectively activating the estrogen receptor ERβ.
Allotetrahydrocorticosterone (600-63-5)  
tetrahydrocorticosterone, (3beta,5alpha,11beta)-isomer  ·  3 beta,11 beta,21-trihydroxy-5 alpha-pregnan-20-one  ·  allopregnane-3 beta,11 beta,21-triol-20-one
17-Deoxycortisone (72-23-1)  
11-dehydrocorticosterone  ·  11-dehydrocorticosterone, 4-(14)C labeled
11-Dehydrocorticosterone (11-DHC), also known as 11-oxocorticosterone or 17-deoxycortisone, as well as 21-hydroxypregn-4-ene-3,11,20-trione, is a naturally occurring, endogenous corticosteroid related to cortisone and corticosterone. It is a potent mineralocorticoid, with generally greater such activity than that of corticosterone.
3,4-Dihydro-2H-phenanthren-1-one (573-22-8)  
1-Keto-1,2,3,4-tetrahydrophenanthrene (THP-1), or 1,2,3,4-tetrahydrophenanthren-1-one, is a synthetic steroid-like compound which was reported to be the first synthetic estrogen, or the first synthetic compound identified with estrogenic activity. It was first synthesized in 1933 by Cook et al. and was tested due to its similarity to the presumed chemical structure of estrone.
Tetrahydrocorticosterone (68-42-8)  
tetrahydrocorticosterone, (3beta,5alpha,11beta)-isomer  ·  3 beta,11 beta,21-trihydroxy-5 alpha-pregnan-20-one  ·  allopregnane-3 beta,11 beta,21-triol-20-one
3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone.
11-DEHYDROCORTICOSTERONE (72-23-1)  
11-dehydrocorticosterone, 4-(14)C labeled
11-Dehydrocorticosterone (11-DHC), also known as 11-oxocorticosterone or 17-deoxycortisone, as well as 21-hydroxypregn-4-ene-3,11,20-trione, is a naturally occurring, endogenous corticosteroid related to cortisone and corticosterone. It is a potent mineralocorticoid, with generally greater such activity than that of corticosterone.
BOMT (24543-59-7)  
BOMT (developmental code name Ro 7-2340), also known as 6α-bromo-4-oxa-17α-methyl-5α-dihydrotestosterone, is a synthetic, steroidal, pure antiandrogen that was first developed in 1970 and was never marketed for clinical use. It is the 6α-brominated, 4-oxygenated, and 17α-methylated derivative of dihydrotestosterone (DHT). Along with benorterone, cyproterone (and its acetate ester, cyproterone acetate), and flutamide, BOMT was among the earliest antiandrogens to be developed and extensively studied, although it is less well-documented in comparison to the others.
17-Methylprogesterone (1046-28-2)  
17α-Methylprogesterone (17α-MP), or 17α-methylpregn-4-ene-3,20-dione, is a steroidal progestin related to progesterone that was synthesized and characterized in 1949 but was never marketed. Along with ethisterone (1938) and 19-norprogesterone (1951), 17α-MP was one of the earliest derivatives of progesterone to be identified as possessing progestogenic activity. Similarly to progesterone and derivatives like 17α-hydroxyprogesterone and 19-norprogesterone, 17α-MP was found to possess poor (though not negligible) oral bioavailability, but showed improved progestogenic activity relative to progesterone when administered via other routes (e.g., subcutaneous or vaginal).
Dimepregnen (21208-26-4)  
Dimepregnen (INN, BAN) (developmental code name ST-1411), or 6α,16α-dimethylpregn-4-en-3β-ol-20-one, is a pregnene steroid described as an antiestrogen that was synthesized in 1968 and was never marketed. It is similar in structure to the progestins and progesterone derivatives melengestrol and anagestone.
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Ketones
Hormonal agents