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Phenethylamines, Psychoanaleptics

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bupropion (34841-39-9, 34911-55-2)  
Wellbutrin  ·  Bupropion Hydrochloride  ·  Quomen
Bupropion is a medication primarily used as an antidepressant and smoking cessation aid. It is marketed as Wellbutrin and Zyban among other trade names. It is one of the most frequently prescribed antidepressants in the United States and Canada, although in many countries this is an off-label use.
dextroamphetamine (51-64-9)  
Dexedrine  ·  Dextroamphetamine Sulfate  ·  Dexamphetamine
Dextroamphetamine is a potent central nervous system (CNS) stimulant and amphetamine enantiomer that is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used as an athletic performance and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. Dextroamphetamine was also used by military air and tank forces as a 'go-pill' during fatigue-inducing missions such as night-time bombing missions.
AMPHETAMINE (60-15-1, 300-62-9)  
Amphetamine Sulfate  ·  Levoamphetamine  ·  Phenamine
Amphetamine (contracted from alpha-methylphenethylamine) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers, levoamphetamine and dextroamphetamine, in their pure amine forms.
phenylpropanolamine (36393-56-3, 48115-38-4, 14838-15-4, 37577-28-9)  
Phenylpropanolamine Hydrochloride  ·  Norephedrine  ·  Dexatrim
Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs.
methylphenidate (113-45-1)  
Ritalin  ·  Concerta  ·  Methylphenidate Hydrochloride
Methylphenidate, sold under various trade names, Ritalin being one of the most commonly known, is a central nervous system (CNS) stimulant of the phenethylamine and piperidine classes that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. The original patent was owned by CIBA, now Novartis Corporation. It was first licensed by the US Food and Drug Administration (FDA) in 1955 for treating what was then known as hyperactivity.
METHAMPHETAMINE (51-57-0, 537-46-2)  
Desoxyn  ·  Methylamphetamine  ·  Methamphetamine Hydrochloride
Methamphetamine (contracted from N-methylamphetamine) is a strong central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. Methamphetamine properly refers to a specific chemical, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms.
(-)-Norephedrine (492-41-1, 14838-15-4, 700-65-2)  
Phenylpropanolamine  ·  Phenylpropanolamine Hydrochloride  ·  Norephedrine
(-)-NORPSEUDOEPHEDRINE (36393-56-3, 53643-20-2, 37577-07-4)  
L-Norpseudoephedrine, or (−)-norpseudoephedrine, is a psychostimulant drug of the amphetamine family. It is one of the four optical isomers of phenylpropanolamine, the other three being cathine ((+)-norpseudoephedrine), (−)-norephedrine, and (+)-norephedrine; as well as one of the two enantiomers of norpseudoephedrine (the other, of course, being cathine). Similarly to cathine, L-norpseudoephedrine acts as a releasing agent of norepinephrine (EC50 = 30 nM) and to a lesser extent of dopamine (EC50 = 294 nM).
Norephedrine (36393-56-3, 14838-15-4, 37577-28-9, 700-65-2)  
Phenylpropanolamine  ·  Phenylpropanolamine Hydrochloride  ·  Dexatrim
Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs.
DIETHYLPROPION (39648-50-5, 39648-49-2, 90-84-6, 134-80-5)  
Tenuate  ·  Tepanil  ·  Diethylpropion Hydrochloride
Amfepramone is a stimulant drug of the phenethylamine, amphetamine, and cathinone classes that is used as an appetite suppressant. It is used in the short-term management of obesity, along with dietary and lifestyle changes. Amfepramone is most closely chemically related to the antidepressant and smoking cessation aid bupropion (previously called amfebutamone), which has also been developed as a weight-loss medicine when in a combination product with naltrexone.
DL-Methamphetamine (4846-07-5, 7632-10-2, 51-57-0)  
Methamphetamine  ·  Desoxyn  ·  Methylamphetamine
Methamphetamine (contracted from N-methylamphetamine) is a strong central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. Methamphetamine was discovered in 1893 and exists as two enantiomers: levo-methamphetamine and dextro-methamphetamine. Methamphetamine properly refers to a specific chemical, the racemic free base, which is an equal mixture of levomethamphetamine and dextromethamphetamine in their pure amine forms.
Benzfetamine (156-08-1, 101-47-3)  
Benzphetamine  ·  Didrex
Benzphetamine (brand name Didrex) is a substituted amphetamine used short-term along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program for weight loss. It is prescribed for obesity in individuals who have been unable to lose weight through exercise and dieting alone. It is a prodrug to amphetamine.
phenmetrazine (134-49-6)  
Preludin  ·  Phenmetrazine Hydrochloride  ·  Defenmetrazin
Phenmetrazine (INN, USAN, BAN) (brand name Preludin, and many others) is a stimulant drug that was previously used as an appetite suppressant, but has since been withdrawn from the market. It was initially replaced by its analogue phendimetrazine which functions as a prodrug to phenmetrazine, but now it is rarely prescribed, due to concerns of abuse and addiction. Chemically, phenmetrazine is a substituted amphetamine with a morpholine ring.
Phenethylamine (64-04-0)  
2-phenethylamine  ·  phenethylamine hydrobromide  ·  phenethylamine sulfate (2:1)
Phenethylamine (PEA), also known as β-phenylethylamine (β-PEA) and 2-phenylethan-1-amine, is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans. Phenylethylamine functions as a monoaminergic neuromodulator and, to a lesser extent, a neurotransmitter in the human central nervous system. It is biosynthesized from the amino acid L-phenylalanine by enzymatic decarboxylation via the enzyme aromatic L-amino acid decarboxylase.
Dexmethylphenidate (40431-64-9)  
Dexmethylphenidate, sold under the trade names Focalin among others, is a central nervous system (CNS) stimulant used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is in the phenethylamine and piperidine classes of medications. It is the active dextrorotatory enantiomer of methylphenidate.
FENETHYLLINE (3736-08-1)  
Fenethylline (BAN, USAN) is a codrug of amphetamine and theophylline which behaves as a prodrug to both of the aforementioned drugs. It is also spelled phenethylline and fenetylline (INN); other names for it are amphetaminoethyltheophylline and amfetyline. The drug was marketed for use as a psychostimulant under the brand names Captagon, Biocapton, and Fitton.
Cathine (36393-56-3, 492-39-7, 37577-28-9)  
norpseudoephedrine  ·  norpseudoephedrine, (R*,S*)-isomer  ·  norpseudoephedrine, conjugate monoacid, (R-(R*,S*))-isomer
Cathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which acts as a stimulant. Along with cathinone, it is found naturally in Catha edulis (khat), and contributes to its overall effects. It has approximately 10-14% the potency of amphetamine.
Levamfetamine (156-34-3, 41820-21-7)  
Amphetamine  ·  Amphetamine Sulfate  ·  Levoamphetamine
Levoamphetamine is a central nervous system (CNS) stimulant known to increase wakefulness and concentration in association with decreased appetite and fatigue. Pharmaceuticals that contain levoamphetamine are currently indicated and prescribed for the treatment of attention deficit hyperactivity disorder (ADHD), obesity, and narcolepsy in some countries. Levoamphetamine is the levorotatory stereoisomer of the amphetamine molecule.
Methylephedrine (552-79-4, 42151-56-4)  
methylpseudoephedrine  ·  N-methylephedrine hydrochloride, (R*,S*)-isomer  ·  N-methylephedrine hydrochloride, (R*,R*)-(+-)-isomer
Prolintane (493-92-5)  
1-(alpha-propylphenethyl)pyrrolidine  ·  Promotil  ·  phenylpyrrolidinylpentan
Prolintane (Catovit, Katovit, Promotil, Villescon) is a stimulant and norepinephrine-dopamine reuptake inhibitor developed in the 1950s. It is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and it has a similar mechanism of action. Many cases of prolintane abuse have been reported.
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