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Piperidines, Antiemetics


Cyclic compounds (4)
Drugs acting on the gastrointestinal system and metabolism (4)
Six-membered rings (4)
Aromatic compounds (3)
Chloroarenes (3)
Dopamine antagonists (3)
Drugs acting on the nervous system (3)
Psychoactive drugs (3)
Gastrointestinal system drug (2)
Motility stimulants (2)
Pharmaceuticals (2)
Alcohols (1)
Antiarrhythmic agents (1)
Antipsychotics (1)
Drugs acting on the cardiovascular system (1)
Fluoroarenes (1)
Potassium channel blockers (1)
Psychopharmacology (1)
Typical antipsychotics (1)
Ureas (1)


Sigma Aldrich (3)
TCI Chemicals (2)
Matrix Scientific (1)

haloperidol (61788-97-4, 52-86-8)  
Haloperidol, marketed under the trade name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia, tics in Tourette syndrome, mania in bipolar disorder, nausea and vomiting, delirium, agitation, acute psychosis, and hallucinations in alcohol withdrawal. It may be used by mouth, as an injection into a muscle, or intravenously.
domperidone (57808-66-9)  
Motilium  ·  Apo-Domperidone  ·  Gastrocure
Domperidone, sold under the brand name Motilium among others, is a peripherally selective dopamine D2 receptor antagonist that was developed by Janssen Pharmaceutica and is used as an antiemetic, gastroprokinetic agent, and galactagogue. It may be administered orally or rectally, and is available in the form of tablets, orally disintegrating tablets (based on Zydis technology), suspension, and suppositories. The drug is used to relieve nausea and vomiting; to increase the transit of food through the stomach (by increasing gastrointestinal peristalsis); and to promote lactation (breast milk production) by release of prolactin.
Metopimazine (14008-44-7)  
metopimazine hydrochloride  ·  1-(3-(2-methylsulfonylphenothiazin-10-yl) propyl)isonipecotinamide  ·  Vogalene
Metopimazine (INN) is a phenothiazine antiemetic.
Clebopride (55905-53-8)  
clebopride maleate (1:1)  ·  clebopride maleate  ·  clebopride fumarate (1:1)
Clebopride is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Chemically, it is a substituted benzamide, closely related to metoclopramide. A small Spanish study found that more adverse reactions are reported with clebopride than with metoclopramide, particularly extrapyramidal symptoms.
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