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Piperidines, Carboxylic acids


Acids (9)
Cyclic compounds (9)
Organic acids (9)
Six-membered rings (9)
Drugs acting on the nervous system (4)
Psychoactive drugs (3)
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Five-membered rings (1)
Loop diuretics (1)
Nervous system drug (1)
Opioid receptor ligands (1)
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fexofenadine (83799-24-0)  
Allegra  ·  fexofenadine hydrochloride  ·  Aventis brand of fexofenadine hydrochloride
Fexofenadine, sold under the trade name Allegra among others is an antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria. Therapeutically, fexofenadine is a selective peripheral H1-blocker. Fexofenadine is classified as a second-generation antihistamine because it is less able to pass the blood-brain barrier and cause sedation, compared to first-generation antihistamines.
piperidine-2-carboxylic acid (535-75-1, 4043-87-2)  
pipecolic acid  ·  pipecolic acid, (R)-isomer  ·  pipecolic acid, (+,-)-isomer
Pipecolic acid (piperidine-2-carboxylic acid) is a small organic molecule which accumulates in pipecolic acidemia. It is a carboxylic acid of piperidine.
l-Pipecolic acid (3105-95-1)  
pipecolic acid  ·  pipecolic acid, (R)-isomer  ·  pipecolic acid, (+,-)-isomer
Bilastine (202189-78-4)  
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives). It exerts its effect as a selective histamine H1 receptor antagonist, and has an effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.
Selfotel (113229-62-2, 110347-85-8)  
Selfotel (CGS-19755) is a drug which acts as a competitive NMDA antagonist, directly competing with glutamate for binding to the receptor. Initial studies showed it to have anticonvulsant, anxiolytic, analgesic and neuroprotective effects, and it was originally researched for the treatment of stroke, but subsequent animal and human studies showed phencyclidine-like effects, as well as limited efficacy and evidence for possible neurotoxicity under some conditions, and so clinical development was ultimately discontinued.
Meperidinic acid (3627-48-3)  
Pethidinic acid (meperidinic acid, pethidine intermediate C) is a 4-phenylpiperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine). It is scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9234.
Ozolinone (56784-39-5)  
3-methyl-4-oxo-5-piperidinothiazolidine-2-ylidine acetic acid  ·  ozolinone, (Z)-(-)-isomer  ·  ozolinone, (Z)-(+)-isomer
Ozolinone is a loop diuretic which was never marketed. It is an active metabolite of etozoline.
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Carboxylic acids