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Piperidines, Dibenzazepines


Antipsychotics (3)
Aromatic compounds (3)
Atypical antipsychotics (3)
Cyclic compounds (3)
Dopamine antagonists (3)
Drugs acting on the nervous system (3)
Psychoactive drugs (3)
Psychopharmacology (3)
Six-membered rings (3)
Chloroarenes (1)
Pyridines (1)
Spiro compounds (1)

Clocapramine (47739-98-0, 28058-62-0)  
Y-4153  ·  3-chlorocarpipramine  ·  3-chlorocarpipramine dihydrochloride
Clocapramine (Clofekton, Padrasen), also known as 3-chlorocarpipramine, is an atypical antipsychotic of the imidobenzyl class which was introduced in Japan in 1974 by Yoshitomi for the treatment of schizophrenia. In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic. Clocapramine has been reported to act as an antagonist of the D2, 5-HT2A, α1-adrenergic, and α2-adrenergic receptors, and does not inhibit the reuptake of either serotonin or norepinephrine.
carpipramine (5942-95-0)  
carbadipimidine  ·  carpipramine dihydrochloride  ·  Prazinil
Carpipramine (Prazinil, Defekton) is an atypical antipsychotic used for the treatment of schizophrenia and anxiety in France and Japan. In addition to its neuroleptic and anxiolytic effects, carpipramine also has hypnotic properties. It is structurally related to both tricyclics like imipramine and butyrophenones like haloperidol.
Mosapramine (89419-40-9)  
3-chloro-5-(3-(2-oxo-1,2,3,5,6,7,8,8a-octahydroimidazo(1,2-a)pyridine-3-spiro-4'-piperidino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine  ·  Y 516  ·  Y-516
Mosapramine (Cremin) is an atypical antipsychotic used in Japan. It is a potent dopamine antagonist with high affinity to the D2, D3, and D4 receptors, and with moderate affinity for the 5-HT2 receptors.
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